| Descriptor English: | Caspase 9 | ||||||
| Descriptor Spanish: |
Caspasa 9
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| Descriptor Portuguese: | Caspase 9 | ||||||
| Descriptor French: | Caspase-9 | ||||||
| Entry term(s): |
Apoptotic Protease Activating Factor 3 Caspase-9 ICE LAP6 Protein ICE Like Apoptotic Protease 6 ICE-LAP6 Protein ICE-Like Apoptotic Protease 6 Pro Caspase 9 Pro-Caspase-9 Procaspase 9 Procaspase-9 |
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| Tree number(s): |
D08.811.277.656.262.500.126.550.900 D08.811.277.656.300.200.126.550.900 D12.776.157.057.006.155 D12.776.476.024.139.155 D12.776.476.075.358.155 D12.776.476.075.405.550.900 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D053453 | ||||||
| Scope note: | A long pro-domain caspase that contains a CASPASE RECRUITMENT DOMAIN in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES. |
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| Annotation: | Do not confuse with CAS9 ENZYME see CRISPR-ASSOCIATED PROTEIN 9 |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Entry Combination: |
antagonists & inhibitors:Caspase Inhibitors
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| Registry Number: | EC 3.4.22.- | ||||||
| Public MeSH Note: | 2007; CASPASE 9 was indexed under CASPASES 1999-2005, & under CYSTEINE PROTEINASES 1996-1998 |
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| History Note: | 2007(2005) |
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| DeCS ID: | 52228 | ||||||
| Unique ID: | D053453 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2007/01/01 | ||||||
| Date of Entry: | 2006/07/05 | ||||||
| Revision Date: | 2016/07/05 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
|
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Caspase 9
- Preferred
Procaspase-9
- Narrower
| Concept UI |
M0264023 |
| Scope note | A long pro-domain caspase that contains a CASPASE RECRUITMENT DOMAIN in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES. |
| Preferred term | Caspase 9 |
| Entry term(s) |
Apoptotic Protease Activating Factor 3 Caspase-9 ICE LAP6 Protein ICE Like Apoptotic Protease 6 ICE-LAP6 Protein ICE-Like Apoptotic Protease 6 |
| Concept UI |
M0296645 |
| Preferred term | Procaspase-9 |
| Entry term(s) |
Pro Caspase 9 Pro-Caspase-9 Procaspase 9 |
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