| Descriptor English: | Sirtuin 3 | ||||||
| Descriptor Spanish: |
Sirtuina 3
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| Descriptor Portuguese: | Sirtuína 3 | ||||||
| Descriptor French: | Sirtuine-3 | ||||||
| Entry term(s): |
Silent Mating Type Information Regulation 2 Homolog 3 Sirt3 |
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| Tree number(s): |
D08.811.277.087.520.200.650.600 D08.811.913.400.725.115.961.600 D12.776.476.900.600 D12.776.575.875 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D056566 | ||||||
| Scope note: | A sirtuin family member found primarily in MITOCHONDRIA. It is a multifunctional enzyme that contains a NAD-dependent deacetylase activity that is specific for HISTONES and a mono-ADP-ribosyltransferase activity. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 3.5.1.- | ||||||
| Previous Indexing: |
Histone Deacetylases (2002-2005) Mitochondrial Proteins (2006-2009) Sirtuins (2006-2009) |
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| Public MeSH Note: | 2010 |
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| History Note: | 2010 |
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| DeCS ID: | 53589 | ||||||
| Unique ID: | D056566 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2010/01/01 | ||||||
| Date of Entry: | 2009/07/06 | ||||||
| Revision Date: | 2018/06/14 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Sirtuin 3
- Preferred
| Concept UI |
M0527794 |
| Scope note | A sirtuin family member found primarily in MITOCHONDRIA. It is a multifunctional enzyme that contains a NAD-dependent deacetylase activity that is specific for HISTONES and a mono-ADP-ribosyltransferase activity. |
| Preferred term | Sirtuin 3 |
| Entry term(s) |
Silent Mating Type Information Regulation 2 Homolog 3 Sirt3 |
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