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Descriptor English: Mitochondrial Processing Peptidase
Descriptor Spanish: Peptidasa de Procesamiento Mitocondrial
Descriptor peptidasa procesadora mitocondrial
Entry term(s) MPP alfa
MPP beta
peptidasa procesadora de la matriz
proteasa de procesamiento mitocondrial
Scope note: Proteína heterodimérica formada por dos subunidades, alfa y beta, denominadas PMPCA y PMPCB en los seres humanos. Tiene una función esencial en la eliminación de péptidos direccionales aminoterminales de las proteínas precursoras importadas a las mitocondrias.
Descriptor Portuguese: Peptidase de Processamento Mitocondrial
Descriptor French: Without translation
Entry term(s): Matrix Processing Peptidase
Mitochondrial Processing Protease
Peptidase, Matrix Processing
Peptidase, Mitochondrial Processing
Processing Peptidase, Matrix
Processing Peptidase, Mitochondrial
Processing Protease, Mitochondrial
Protease, Mitochondrial Processing
alpha MPP
alpha-MPP
beta MPP
beta-MPP
Tree number(s): D08.811.277.656.300.480.563
D08.811.277.656.675.374.563
D12.776.575.758
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000096122
Scope note: A hetero-dimeric protein consisting of two subunits, alpha and beta, which are referred to as PMPCA and PMPCB in humans. It plays an essential role in removing the N-terminal targeting peptidase from precursor proteins imported into the mitochondria.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.4.24.64
Public MeSH Note: 2024; MITOCHONDRIAL PROCESSING PEPTIDASE was indexed under METALLOENDOPEPTIDASES, 1990-2023
History Note: 2024 (1990)
DeCS ID: 60467
Unique ID: D000096122
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/05/22
Mitochondrial Processing Peptidase - Preferred
Concept UI M0177633
Scope note A hetero-dimeric protein consisting of two subunits, alpha and beta, which are referred to as PMPCA and PMPCB in humans. It plays an essential role in removing the N-terminal targeting peptidase from precursor proteins imported into the mitochondria.
Preferred term Mitochondrial Processing Peptidase
Entry term(s) Matrix Processing Peptidase
Mitochondrial Processing Protease
Peptidase, Matrix Processing
Peptidase, Mitochondrial Processing
Processing Peptidase, Matrix
Processing Peptidase, Mitochondrial
Processing Protease, Mitochondrial
Protease, Mitochondrial Processing
beta-MPP - Narrower
Concept UI M0177630
Preferred term beta-MPP
Entry term(s) beta MPP
alpha-MPP - Narrower
Concept UI M0177629
Preferred term alpha-MPP
Entry term(s) alpha MPP



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