| Descriptor English: | B7-H1 Antigen | ||||||
| Descriptor Spanish: |
Antígeno B7-H1
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| Descriptor Portuguese: | Antígeno B7-H1 | ||||||
| Descriptor French: | Antigène CD274 | ||||||
| Entry term(s): |
Antigen, B7-H1 Antigen, CD274 Antigens, CD274 B7 H1 Antigen B7 H1 Immune Costimulatory Protein B7-H1 Immune Costimulatory Protein B7H1 Immune Costimulatory Protein CD274 Antigen CD274 Antigens Costimulatory Protein, PD-L1 PD L1 Costimulatory Protein PD L1 Protein PD-L1 Costimulatory Protein PD-L1 Protein Programmed Cell Death 1 Ligand 1 Programmed Cell Death 1 Ligand 1 Protein Programmed Death Ligand 1 |
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| Tree number(s): |
D12.776.465.625 D12.776.467.150.300 D12.776.543.095.300 D23.050.301.285.400 D23.529.168.300 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D060890 | ||||||
| Scope note: | An inhibitory B7 antigen that contains V-type and C2 type immunoglobulin domains. It has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN and provides negative signals that control and inhibit T-cell responses. It is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Antigens, CD (2007-2011) Antigens, CD80 (2001-2006) Blood Proteins (2001-2005) |
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| Public MeSH Note: | 2018; see ANTIGENS, CD274 2012-2017 |
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| History Note: | 2018 (2007) |
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| Related: |
Immunoglobulin Domains
MeSH | ||||||
| DeCS ID: | 54623 | ||||||
| Unique ID: | D060890 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2012/01/01 | ||||||
| Date of Entry: | 2011/06/24 | ||||||
| Revision Date: | 2020/03/27 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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B7-H1 Antigen
- Preferred
| Concept UI |
M0555734 |
| Scope note | An inhibitory B7 antigen that contains V-type and C2 type immunoglobulin domains. It has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN and provides negative signals that control and inhibit T-cell responses. It is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION. |
| Preferred term | B7-H1 Antigen |
| Entry term(s) |
Antigen, B7-H1 Antigen, CD274 Antigens, CD274 B7 H1 Antigen B7 H1 Immune Costimulatory Protein B7-H1 Immune Costimulatory Protein B7H1 Immune Costimulatory Protein CD274 Antigen CD274 Antigens Costimulatory Protein, PD-L1 PD L1 Costimulatory Protein PD L1 Protein PD-L1 Costimulatory Protein PD-L1 Protein Programmed Cell Death 1 Ligand 1 Programmed Cell Death 1 Ligand 1 Protein Programmed Death Ligand 1 |
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