| Descriptor English: | Immune Checkpoint Proteins | ||||||
| Descriptor Spanish: |
Proteínas de Punto de Control Inmunitario
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| Descriptor Portuguese: | Proteínas de Checkpoint Imunológico | ||||||
| Descriptor French: | Protéines de points de contrôle immunitaires | ||||||
| Entry term(s): |
Checkpoint Molecule, Immune Checkpoint Molecule, Inhibitory Checkpoint Molecule, Stimulatory Checkpoint Protein, Immune Immune Checkpoint Molecule Immune Checkpoint Molecules Immune Checkpoint Protein Inhibitory Checkpoint Molecule Inhibitory Checkpoint Molecules Molecule, Immune Checkpoint Protein, Immune Checkpoint Stimulatory Checkpoint Molecule Stimulatory Checkpoint Molecules |
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| Tree number(s): |
D12.776.465 D23.383 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000082102 | ||||||
| Scope note: | Immunomodulators that regulate immune system either in stimulatory or inhibitory fashion allowing IMMUNE TOLERANCE. Activation of suppressed immune system (IMMUNOSUPPRESSION (PHYSIOLOGY)) in immunotherapy by IMMUNE CHECKPOINT INHIBITORS often targets inhibitory checkpoint molecules. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Public MeSH Note: | 2021 |
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| History Note: | 2021 |
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| DeCS ID: | 59323 | ||||||
| Unique ID: | D000082102 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2021/01/01 | ||||||
| Date of Entry: | 2020/07/07 | ||||||
| Revision Date: | 2020/05/27 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Immune Checkpoint Proteins
- Preferred
Stimulatory Checkpoint Molecules
- Narrower
Inhibitory Checkpoint Molecules
- Narrower
| Concept UI |
M000675777 |
| Scope note | Immunomodulators that regulate immune system either in stimulatory or inhibitory fashion allowing IMMUNE TOLERANCE. Activation of suppressed immune system (IMMUNOSUPPRESSION (PHYSIOLOGY)) in immunotherapy by IMMUNE CHECKPOINT INHIBITORS often targets inhibitory checkpoint molecules. |
| Preferred term | Immune Checkpoint Proteins |
| Entry term(s) |
Checkpoint Molecule, Immune Checkpoint Protein, Immune Immune Checkpoint Molecule Immune Checkpoint Molecules Immune Checkpoint Protein Molecule, Immune Checkpoint Protein, Immune Checkpoint |
| Concept UI |
M000675778 |
| Preferred term | Stimulatory Checkpoint Molecules |
| Entry term(s) |
Checkpoint Molecule, Stimulatory Stimulatory Checkpoint Molecule |
| Concept UI |
M000675779 |
| Preferred term | Inhibitory Checkpoint Molecules |
| Entry term(s) |
Checkpoint Molecule, Inhibitory Inhibitory Checkpoint Molecule |
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