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Descriptor English: Immune Checkpoint Proteins
Descriptor Spanish: Proteínas de Punto de Control Inmunitario
Descriptor Portuguese: Proteínas de Checkpoint Imunológico
Descriptor French: Without translation
Entry term(s): Checkpoint Molecule, Immune
Checkpoint Molecule, Inhibitory
Checkpoint Molecule, Stimulatory
Checkpoint Protein, Immune
Immune Checkpoint Molecule
Immune Checkpoint Molecules
Immune Checkpoint Protein
Inhibitory Checkpoint Molecule
Inhibitory Checkpoint Molecules
Molecule, Immune Checkpoint
Protein, Immune Checkpoint
Stimulatory Checkpoint Molecule
Stimulatory Checkpoint Molecules
Tree number(s): D12.776.465
D23.383
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000082102
Scope note: Immunomodulators that regulate immune system either in stimulatory or inhibitory fashion allowing IMMUNE TOLERANCE. Activation of suppressed immune system (IMMUNOSUPPRESSION (PHYSIOLOGY)) in immunotherapy by IMMUNE CHECKPOINT INHIBITORS often targets inhibitory checkpoint molecules.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2021
History Note: 2021
DeCS ID: 59323
Unique ID: D000082102
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2021/01/01
Date of Entry: 2020/07/07
Revision Date: 2020/05/27
Immune Checkpoint Proteins - Preferred
Concept UI M000675777
Scope note Immunomodulators that regulate immune system either in stimulatory or inhibitory fashion allowing IMMUNE TOLERANCE. Activation of suppressed immune system (IMMUNOSUPPRESSION (PHYSIOLOGY)) in immunotherapy by IMMUNE CHECKPOINT INHIBITORS often targets inhibitory checkpoint molecules.
Preferred term Immune Checkpoint Proteins
Entry term(s) Checkpoint Molecule, Immune
Checkpoint Protein, Immune
Immune Checkpoint Molecule
Immune Checkpoint Molecules
Immune Checkpoint Protein
Molecule, Immune Checkpoint
Protein, Immune Checkpoint
Stimulatory Checkpoint Molecules - Narrower
Concept UI M000675778
Preferred term Stimulatory Checkpoint Molecules
Entry term(s) Checkpoint Molecule, Stimulatory
Stimulatory Checkpoint Molecule
Inhibitory Checkpoint Molecules - Narrower
Concept UI M000675779
Preferred term Inhibitory Checkpoint Molecules
Entry term(s) Checkpoint Molecule, Inhibitory
Inhibitory Checkpoint Molecule



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