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Descriptor English: Hepcidins
Descriptor Spanish: Hepcidinas
Descriptor hepcidinas
Scope note: Formas de hepcidina, un péptido catiónico anfipático sintetizado en el hígado como prepropéptido, que es primero procesado a prohepcidina y luego a las formas biológicamente activas de hepcidina incluyendo en humanos los péptidos de 20-, 22-, y 25-aminoácidos. La hepcidina actúa como regulador homeostático del metabolismo del hierro y también posee actividad antimicrobiana.
Descriptor Portuguese: Hepcidinas
Descriptor French: Hepcidines
Entry term(s): Hepcidine
Peptide antimicrobien exprimé dans le foie
Pro-hepcidine
Prohepcidine
Tree number(s): D12.776.494.249
D12.776.543.695.054.425
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D064451
Scope note: Forms of hepcidin, a cationic amphipathic peptide synthesized in the liver as a prepropeptide which is first processed into prohepcidin and then into the biologically active hepcidin forms, including in human the 20-, 22-, and 25-amino acid residue peptide forms. Hepcidin acts as a homeostatic regulators of iron metabolism and also possesses antimicrobial activity.
Allowable Qualifiers: AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Anti-Infective Agents
Related: Anémie MeSH
Hémochromatose MeSH
DeCS ID: 55332
Unique ID: D064451
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Hepcidines - Preferred
Concept UI M0581933
Preferred term Hepcidines
Entry term(s) Hepcidine
Peptide antimicrobien exprimé dans le foie
Prohepcidine - Narrower
Concept UI M0501865
Preferred term Prohepcidine
Entry term(s) Pro-hepcidine



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