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Descriptor English: Amitrole
Descriptor Spanish: Amitrol (Herbicida)
Descriptor amitrol (herbicida)
Entry term(s) aminotriazol
Scope note: Herbicida translocado, no selectivo, de postemergencia. De acuerdo con el Séptimo Informe Anual sobre Carcinógenos (PB95-109781, 1994) esta sustancia puede considerarse razonablemente como cancerígena. (Merck Index, 12th ed) Se trata de un inhibidor irreversible de la CATALASA que altera la actividad de los peroxisomas.
Descriptor Portuguese: Amitrol (Herbicida)
Descriptor French: Amitrole
Entry term(s): 3-Amino-1,2,4-triazole
Aminotriazole
Tree number(s): D03.383.129.799.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000640
Scope note: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Enzyme Inhibitors
Registry Number: ZF80H5GXUF
CAS Type 1 Name: 1H-1,2,4-Triazol-3-amine
Previous Indexing: Herbicides (1966-1971)
Triazoles (1966-1971)
Public MeSH Note: 91; was see under TRIAZOLES 1972-90
History Note: 91(72); was see under TRIAZOLES 1972-90
DeCS ID: 653
Unique ID: D000640
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/27
Amitrole - Preferred
Concept UI M0000980
Scope note A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
Preferred term Amitrole
Entry term(s) 3-Amino-1,2,4-triazole
Aminotriazole



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