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Descriptor English: Anastrozole
Descriptor Spanish: Anastrozol
Descriptor Portuguese: Anastrozol
Descriptor French: Anastrozole
Entry term(s): 2,2'-(5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile)
Anastrazole
Arimidex
ICI D1033
ZD 1033
ZD-1033
ZD1033
Zeneca ZD 1033
Tree number(s): D02.626.218
D03.383.129.799.275
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077384
Scope note: A nitrile and triazole derivative that acts as a selective nonsteroidal aromatase inhibitor. It is used in the treatment of ESTROGEN NUCLEAR RECEPTOR-positive breast cancer in postmenopausal women.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antineoplastic Agents, Hormonal
Aromatase Inhibitors
Registry Number: 2Z07MYW1AZ
CAS Type 1 Name: 1,3-Benzenediacetonitrile, alpha,alpha,alpha',alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-
Public MeSH Note: 2019; ANASTROZOLE was indexed under NITRILES and TRIAZOLES 1994-2018
History Note: 2019 (1994)
DeCS ID: 57628
Unique ID: D000077384
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/02/27
Anastrozole - Preferred
Concept UI M0238999
Scope note A nitrile and triazole derivative that acts as a selective nonsteroidal aromatase inhibitor. It is used in the treatment of ESTROGEN NUCLEAR RECEPTOR-positive breast cancer in postmenopausal women.
Preferred term Anastrozole
Entry term(s) 2,2'-(5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile)
Anastrazole
Arimidex - Narrower
Concept UI M0239000
Preferred term Arimidex
ICI D1033 - Narrower
Concept UI M0238995
Preferred term ICI D1033
ZD-1033 - Narrower
Concept UI M0238996
Preferred term ZD-1033
Entry term(s) ZD 1033
ZD1033
Zeneca ZD 1033



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