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Descriptor in English: Deferasirox
Descriptor in Spanish: Deferasirox
Descriptor in Portuguese: Deferasirox
Descriptor in French: Déférasirox
Entry term(s): 4-(3,5-Bis-(2-hydroxyphenyl)-(1,2,4)-triazol-1-yl)benzoic acid
Exjade
ICL 670
ICL 670A
ICL-670
ICL-670A
ICL670
ICL670A
Tree number(s): D02.241.223.100.250
D02.455.426.559.389.127.266
D03.383.129.799.363
Scope note: A triazole and benzoate derivative that acts as a selective iron chelator. It is used in the management of chronic IRON OVERLOAD due to blood transfusion or non-transfusion dependent THALASSEMIA.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 2019 (2000)
DeCS UI: 57695
Descriptor UI: D000077588
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/04/09
Deferasirox - Preferred
Concept UI M0490722
Scope note A triazole and benzoate derivative that acts as a selective iron chelator. It is used in the management of chronic IRON OVERLOAD due to blood transfusion or non-transfusion dependent THALASSEMIA.
Preferred term Deferasirox
Entry term(s) 4-(3,5-Bis-(2-hydroxyphenyl)-(1,2,4)-triazol-1-yl)benzoic acid
ICL 670A - Narrower
Concept UI M000640989
Preferred term ICL 670A
Entry term(s) ICL-670A
ICL670A - Narrower
Concept UI M0372182
Preferred term ICL670A
Entry term(s) ICL 670
ICL-670
ICL670
Exjade - Narrower
Concept UI M0488046
Preferred term Exjade



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