Descriptor English: | Deferasirox | ||||||
Descriptor Spanish: |
Deferasirox
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Descriptor Portuguese: | Deferasirox | ||||||
Descriptor French: | Déférasirox | ||||||
Entry term(s): |
4-(3,5-Bis-(2-hydroxyphenyl)-(1,2,4)-triazol-1-yl)benzoic acid Exjade ICL 670 ICL 670A ICL-670 ICL-670A ICL670 ICL670A |
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Tree number(s): |
D02.241.223.100.250 D02.455.426.559.389.127.266 D03.383.129.799.363 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000077588 | ||||||
Scope note: | A triazole and benzoate derivative that acts as a selective iron chelator. It is used in the management of chronic IRON OVERLOAD due to blood transfusion or non-transfusion dependent THALASSEMIA. |
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Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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Pharm Action: |
Iron Chelating Agents |
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Registry Number: | V8G4MOF2V9 | ||||||
Public MeSH Note: | 2019; DEFERASIROX was indexed under BENZOATES and TRIAZOLES 2000-2018 |
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History Note: | 2019 (2000) |
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DeCS ID: | 57695 | ||||||
Unique ID: | D000077588 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2019/01/01 | ||||||
Date of Entry: | 2018/07/09 | ||||||
Revision Date: | 2018/04/09 |
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CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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Deferasirox
- Preferred
ICL 670A
- Narrower
ICL670A
- Narrower
Exjade
- Narrower
Concept UI |
M0490722 |
Scope note | A triazole and benzoate derivative that acts as a selective iron chelator. It is used in the management of chronic IRON OVERLOAD due to blood transfusion or non-transfusion dependent THALASSEMIA. |
Preferred term | Deferasirox |
Entry term(s) |
4-(3,5-Bis-(2-hydroxyphenyl)-(1,2,4)-triazol-1-yl)benzoic acid |
Concept UI |
M000640989 |
Preferred term | ICL 670A |
Entry term(s) |
ICL-670A |
Concept UI |
M0372182 |
Preferred term | ICL670A |
Entry term(s) |
ICL 670 ICL-670 ICL670 |
Concept UI |
M0488046 |
Preferred term | Exjade |
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