Descriptor English: | Tubulin | ||||||
Descriptor Spanish: |
Tubulina (Proteína)
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Descriptor Portuguese: | Tubulina (Proteína) | ||||||
Descriptor French: | Tubuline | ||||||
Entry term(s): |
alpha Tubulin alpha-Tubulin beta Tubulin beta-Tubulin delta Tubulin delta-Tubulin epsilon Tubulin epsilon-Tubulin gamma Tubulin gamma-Tubulin |
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Tree number(s): |
D05.750.078.734.800 D12.776.220.600.800 D12.776.631.920 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D014404 | ||||||
Scope note: | A microtubule subunit protein found in large quantities in mammalian brain. It has also been isolated from SPERM FLAGELLUM; CILIA; and other sources. Structurally, the protein is a dimer with a molecular weight of approximately 120,000 and a sedimentation coefficient of 5.8S. It binds to COLCHICINE; VINCRISTINE; and VINBLASTINE. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Entry Combination: |
antagonists & inhibitors:Tubulin Modulators
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Previous Indexing: |
Microtubules (1970-1974) Nerve Tissue Proteins (1966-1974) |
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Public MeSH Note: | 80; was see under GLYCOPROTEINS 1975-79 |
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History Note: | 80(75); was see under GLYCOPROTEINS 1975-79 |
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DeCS ID: | 14806 | ||||||
Unique ID: | D014404 | ||||||
NLM Classification: | QU 55.3 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1980/01/01 | ||||||
Date of Entry: | 1974/11/11 | ||||||
Revision Date: | 2015/11/24 |
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CHEMICALS AND DRUGS
Macromolecular Substances [D05]Macromolecular Substances -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Tubulin
- Preferred
gamma-Tubulin
- Narrower
delta-Tubulin
- Narrower
epsilon-Tubulin
- Narrower
alpha-Tubulin
- Narrower
beta-Tubulin
- Narrower
Concept UI |
M0022142 |
Scope note | A microtubule subunit protein found in large quantities in mammalian brain. It has also been isolated from SPERM FLAGELLUM; CILIA; and other sources. Structurally, the protein is a dimer with a molecular weight of approximately 120,000 and a sedimentation coefficient of 5.8S. It binds to COLCHICINE; VINCRISTINE; and VINBLASTINE. |
Preferred term | Tubulin |
Concept UI |
M0022141 |
Preferred term | gamma-Tubulin |
Entry term(s) |
gamma Tubulin |
Concept UI |
M0514734 |
Preferred term | delta-Tubulin |
Entry term(s) |
delta Tubulin |
Concept UI |
M0514735 |
Preferred term | epsilon-Tubulin |
Entry term(s) |
epsilon Tubulin |
Concept UI |
M0022139 |
Preferred term | alpha-Tubulin |
Entry term(s) |
alpha Tubulin |
Concept UI |
M0022140 |
Preferred term | beta-Tubulin |
Entry term(s) |
beta Tubulin |
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