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Descriptor English: GAP-43 Protein
Descriptor Spanish: Proteína GAP-43
Descriptor proteína GAP-43
Entry term(s) GAP-43
neuromodulina
proteína 43 asociada a crecimiento
proteína B-50
proteína de membrana GAP-43 en cono de crecimiento del nervio
Scope note: Proteína específica del tejido nervioso que se expresa ampliamente en las neuronas durante el desarrollo y la regeneración nerviosa. Se la ha implicado en el crecimiento de las neuritas, la potenciación a largo plazo, la TRANSDUCCIÓN DE SEÑAL y la liberación de NEUROTRANSMISORES (Neurotoxicology 1994;15(1):41-7). También es un sustrato de la PROTEINCINASA C.
Descriptor Portuguese: Proteína GAP-43
Descriptor French: Protéine GAP-43
Entry term(s): B 50 Protein
B-50 Protein
GAP 43 Protein
GAP-43
GAP43 Protein
Growth Associated Protein 43
Growth-Associated Protein 43
Nerve Growth Cone Membrane Protein GAP 43
Nerve Growth Cone Membrane Protein GAP-43
Neuromodulin
Phosphoprotein B 50
Phosphoprotein B-50
Phosphoprotein F1
Phosphoprotein pp46
Tree number(s): D09.400.430.890.400
D12.776.395.550.400
D12.776.543.550.400
D12.776.631.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019922
Scope note: A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. It has been implicated in neurite outgrowth, long-term potentiation, SIGNAL TRANSDUCTION, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of PROTEIN KINASE C.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Calmodulin-Binding Proteins (1986-1992)
Membrane Glycoproteins (1988-1997)
Membrane Proteins (1986-1989)
Nerve Tissue Proteins (1986-1997)
Public MeSH Note: 98; NERVE GROWTH CONE MEMBRANE PROTEIN GAP-43 (now GAP-43 PROTEIN) was indexed under NERVE TISSUE PROTEINS 1986-97, MEMBRANE GLYCOPROTEINS 1988-97, CALMODULIN-BINDING PROTEINS 1986-92, & MEMBRANE PROTEINS 1986-89.
History Note: 98; use GAP-43 PROTEIN (NM) 1986-97
DeCS ID: 33491
Unique ID: D019922
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2015/11/23
GAP-43 Protein - Preferred
Concept UI M0029597
Scope note A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. It has been implicated in neurite outgrowth, long-term potentiation, SIGNAL TRANSDUCTION, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of PROTEIN KINASE C.
Preferred term GAP-43 Protein
Entry term(s) B 50 Protein
B-50 Protein
GAP 43 Protein
GAP-43
GAP43 Protein
Growth Associated Protein 43
Growth-Associated Protein 43
Nerve Growth Cone Membrane Protein GAP 43
Nerve Growth Cone Membrane Protein GAP-43
Neuromodulin
Phosphoprotein B 50
Phosphoprotein B-50
Phosphoprotein F1
Phosphoprotein pp46



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