Descriptor English: | Disks Large Homolog 4 Protein | ||||||
Descriptor Spanish: |
Homólogo 4 de la Proteína Discs Large
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Descriptor Portuguese: | Proteína 4 Homóloga a Disks-Large | ||||||
Descriptor French: | Homologue-4 de la protéine Disks Large | ||||||
Entry term(s): |
Discs Large Homolog 4 Protein PSD 95 Protein PSD-95 Protein PSD95 Protein Postsynaptic Density Protein 95 SAP 90 Protein SAP-90 Protein SAP90 Protein Synapse Associated Protein 90 Synapse-Associated Protein 90 |
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Tree number(s): |
D08.811.913.696.650.450.750 D12.644.360.265 D12.776.476.265 D12.776.543.219 D12.776.631.224 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000076122 | ||||||
Scope note: | A neuronal protein consisting of three PDZ DOMAINS, an SH3 DOMAIN, and a C-terminal guanylate kinase-like region (see MAGUK PROTEINS). It localizes to the POST-SYNAPTIC DENSITY and associates with the cytoplasmic tail of NMDA RECEPTORS and SHAKER POTASSIUM CHANNELS, playing a critical role in NMDA receptor-mediated SYNAPTIC PLASTICITY. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Previous Indexing: |
Intracellular Signaling Peptides and Proteins (2005-2017) Membrane Proteins (2005-2017) |
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Public MeSH Note: | 2018 |
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History Note: | 2018 |
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Related: |
SAP90-PSD95 Associated Proteins
MeSH | ||||||
DeCS ID: | 57036 | ||||||
Unique ID: | D000076122 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2018/01/01 | ||||||
Date of Entry: | 2017/07/11 | ||||||
Revision Date: | 2017/06/29 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Disks Large Homolog 4 Protein
- Preferred
Concept UI |
M000632224 |
Scope note | A neuronal protein consisting of three PDZ DOMAINS, an SH3 DOMAIN, and a C-terminal guanylate kinase-like region (see MAGUK PROTEINS). It localizes to the POST-SYNAPTIC DENSITY and associates with the cytoplasmic tail of NMDA RECEPTORS and SHAKER POTASSIUM CHANNELS, playing a critical role in NMDA receptor-mediated SYNAPTIC PLASTICITY. |
Preferred term | Disks Large Homolog 4 Protein |
Entry term(s) |
Discs Large Homolog 4 Protein PSD 95 Protein PSD-95 Protein PSD95 Protein Postsynaptic Density Protein 95 SAP 90 Protein SAP-90 Protein SAP90 Protein Synapse Associated Protein 90 Synapse-Associated Protein 90 |
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