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Descriptor English: Benzopyrene Hydroxylase
Descriptor Spanish: Benzopireno Hidroxilasa
Descriptor benzopireno hidroxilasa
Entry term(s) benzopireno-3 monooxigenasa
benzopireno-hidroxilasa
Scope note: Enzima del citocromo P-448 (P-450), metabolizadora de fármacos, que cataliza la hidroxilación del benzopireno para dar lugar a 3-hidroxibenzopireno, en presencia de flavoproteína reducida y oxígeno molecular. También actúa sobre ciertos derivados antracénicos. Un aspecto de EC 1.14.14.1.
Descriptor Portuguese: Benzopireno Hidroxilase
Descriptor French: Benzopyrene hydroxylase
Entry term(s): Benzo(a)pyrene Hydroxylase
Benzo(a)pyrene Monooxygenase
Benzopyrene 3 Monooxygenase
Benzopyrene-3-Monooxygenase
Hydroxylase, Benzopyrene
Tree number(s): D08.244.453.005.110
D08.811.682.690.708.170.010.110
D12.776.422.220.453.010.110
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001579
Scope note: A drug-metabolizing, cytochrome P-448 (P-450) enzyme which catalyzes the hydroxylation of benzopyrene to 3-hydroxybenzopyrene in the presence of reduced flavoprotein and molecular oxygen. Also acts on certain anthracene derivatives. An aspect of EC 1.14.14.1.
Annotation: a cytochrome
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.14.14.-
Previous Indexing: Benzopyrenes (1968-1974)
Hydroxylases (1968-1974)
Public MeSH Note: 91; was see under ARYL HYDROCARBON HYDROXYLASES 1977-90; was see under HYDROXYLASES 1975-76
History Note: 91(75); was see under ARYL HYDROCARBON HYDROXYLASES 1977-90; was see under HYDROXYLASES 1975-76
DeCS ID: 23168
Unique ID: D001579
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/11
Revision Date: 2016/05/27
Benzopyrene Hydroxylase - Preferred
Concept UI M0002368
Scope note A drug-metabolizing, cytochrome P-448 (P-450) enzyme which catalyzes the hydroxylation of benzopyrene to 3-hydroxybenzopyrene in the presence of reduced flavoprotein and molecular oxygen. Also acts on certain anthracene derivatives. An aspect of EC 1.14.14.1.
Preferred term Benzopyrene Hydroxylase
Entry term(s) Benzo(a)pyrene Hydroxylase
Benzo(a)pyrene Monooxygenase
Benzopyrene 3 Monooxygenase
Benzopyrene-3-Monooxygenase
Hydroxylase, Benzopyrene



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