Search
Descriptor English: Cytochrome P-450 CYP1A1
Descriptor Spanish: Citocromo P-450 CYP1A1
Descriptor citocromo P-450 CYP1A1
Entry term(s) CYP1A1
EROD
etoxirresorufina O-desetilasa
Scope note: Monooxigenasa del citocromo P-450 microsómico hepático, capaz de hacer la biotransformación xenobiótica de hidrocarburos policíclicos e hidrocarburos aromáticos halogenados, dando lugar a compuestos carcinógenos o mutágenos. Se han encontrado en mamíferos y en peces. Esta enzima, codificada por el gen CYP1A1, puede medirse utilizando la etoxirresorufina como sustrato de la actividad etoxirresorufina O-desetilasa.
Descriptor Portuguese: Citocromo P-450 CYP1A1
Descriptor French: Cytochrome P-450 CYP1A1
Entry term(s): 7-Ethoxyresorufin O-Deethylase
CYP 1A1
CYP1A1
CYP1A1 Protein
Cytochrome P 450 CYP1A1
Cytochrome P450 IA1
EROD
Ethoxyresorufin Dealkylase
Ethoxyresorufin O-Deethylase
Ethylresorufin O-Deethylase
Tree number(s): D08.244.453.005.332
D08.244.453.100.500
D08.811.682.690.708.170.010.277
D08.811.682.690.708.170.020.500
D12.776.422.220.453.010.332
D12.776.422.220.453.100.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019363
Scope note: A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.
Annotation: do not confuse with other cytochrome P-450 CYP's
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.14.14.1
Previous Indexing: Cytochrome P-450 (1982-1996)
Oxazines (1979-1981)
Oxidoreductases (1980-1996)
Public MeSH Note: 97; ETHOXYRESORUFIN O-DEETHYLASE was indexed under CYTOCHROME P-450 1982-96, OXIDOREDUCTASES 1980-96, & OXAZINES 1979-81
Online Note: use CYTOCHROME P-450 CYP1A1 (NM) to search ETHOXYRESORUFIN O-DEETHYLASE 1980-96
History Note: 97; was ETHOXYRESORUFIN O-DEETHYLASE (NM) 1979-96
DeCS ID: 33008
Unique ID: D019363
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1997/01/01
Date of Entry: 1996/06/24
Revision Date: 2016/05/27
Cytochrome P-450 CYP1A1 - Preferred
Concept UI M0028818
Scope note A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.
Preferred term Cytochrome P-450 CYP1A1
Entry term(s) 7-Ethoxyresorufin O-Deethylase
CYP 1A1
CYP1A1
CYP1A1 Protein
Cytochrome P 450 CYP1A1
Cytochrome P450 IA1
EROD
Ethoxyresorufin Dealkylase
Ethoxyresorufin O-Deethylase
Ethylresorufin O-Deethylase



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey