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Descriptor English: Cytochrome P-450 CYP2B6
Descriptor Spanish: Citocromo P-450 CYP2B6
Descriptor citocromo P-450 CYP2B6
Scope note: Subtipo de enzima P-450 que oxida un amplia gama de XENOBIÓTICOS. La expresión de CYP2B6 presenta variaciones individuales a consecuencia de una alta tasa de POLIMORFISMOS GENÉTICOS. Ejemplos de fármacos metabolizados por la CYP2B6 son el BUPROPION, el efavirenz, la CICLOFOSFAMIDA y la MEPERIDINA.
Descriptor Portuguese: Citocromo P-450 CYP2B6
Descriptor French: Cytochrome P-450 CYP2B6
Entry term(s): 1,4 Cineole 2 exo Monooxygenase
1,4-Cineole 2-exo-Monooxygenase
2-exo-Monooxygenase, 1,4-Cineole
CYP2B6
CYP2B6, Cytochrome P-450
CYPIIB6
Cytochrome P 450 CYP2B6
Cytochrome P450 2B6
P-450 CYP2B6, Cytochrome
P450 2B6, Cytochrome
Tree number(s): D08.244.453.005.575
D08.244.453.491.344
D08.811.682.690.708.170.010.575
D08.811.682.690.708.170.450.344
D12.776.422.220.453.010.575
D12.776.422.220.453.491.344
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D065702
Scope note: A cytochrome P450 enzyme subtype that oxidizes a diverse array of XENOBIOTICS. The expression of CYP2B6 varies widely between individuals which is due to the high rate of GENETIC POLYMORPHISMS. Examples of drugs metabolized by CYP2B6 include BUPROPION; efavirenz; CYCLOPHOSPHAMIDE; and MEPERIDINE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Cytochrome P-450 CYP2B6 Inhibitors
Registry Number: EC 1.14.14.1
Public MeSH Note: 2015; CYTOCHROME P-450 CYP2B6 was indexed under ARYL HYDROCARBON HYDROXYLASES 1997-2014
History Note: 2015
DeCS ID: 55606
Unique ID: D065702
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2015/01/01
Date of Entry: 2014/06/26
Revision Date: 2016/05/27
Cytochrome P-450 CYP2B6 - Preferred
Concept UI M0590403
Scope note A cytochrome P450 enzyme subtype that oxidizes a diverse array of XENOBIOTICS. The expression of CYP2B6 varies widely between individuals which is due to the high rate of GENETIC POLYMORPHISMS. Examples of drugs metabolized by CYP2B6 include BUPROPION; efavirenz; CYCLOPHOSPHAMIDE; and MEPERIDINE.
Preferred term Cytochrome P-450 CYP2B6
Entry term(s) 1,4 Cineole 2 exo Monooxygenase
1,4-Cineole 2-exo-Monooxygenase
2-exo-Monooxygenase, 1,4-Cineole
CYP2B6
CYP2B6, Cytochrome P-450
CYPIIB6
Cytochrome P 450 CYP2B6
Cytochrome P450 2B6
P-450 CYP2B6, Cytochrome
P450 2B6, Cytochrome



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