Search
Descriptor English: Cytochrome P-450 CYP1B1
Descriptor Spanish: Citocromo P-450 CYP1B1
Descriptor citocromo P-450 CYP1B1
Scope note: Citocromo P-450 arilhidrocarburo hidroxilasa con especificidad para los ESTRÓGENOS a los que transforma en 4-hidroxiestrógenos. Se ha visto que la CYP1B1 tiene importancia en el DESARROLLO FETAL y que las mutaciones del gen CYP1B1 producen formas congénitas de GLAUCOMA y anomalía de Peters.
Descriptor Portuguese: Citocromo P-450 CYP1B1
Descriptor French: Cytochrome P-450 CYP1B1
Entry term(s): Cytochrome P 450 CYP1B1
Cytochrome P450 CYP1B1
Cytochrome P450, Family 1, Subfamily B, Polypeptide 1
Cytochrome P4501B1
P450 CYP1B1, Cytochrome
Tree number(s): D08.244.453.005.500
D08.244.453.100.875
D08.811.682.690.708.170.010.500
D08.811.682.690.708.170.020.875
D12.776.422.220.453.010.500
D12.776.422.220.453.100.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D065633
Scope note: A cytochrome P450 aryl hydrocarbon hydroxylase that has specificity for ESTROGENS which it converts into 4-hydroxy estrogens. CYP1B1 has been shown to be physiologically important for FETAL DEVELOPMENT with mutations in the CYP1B1 gene resulting in congenital forms of GLAUCOMA and Peter's anomaly.
Annotation: /antag: coordinate with CYTOCHROME P-450 ENZYME INHIBITORS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.14.14.1
Public MeSH Note: 2015; CYTOCHROME P-450 CYPB1 was indexed under ARYL HYDROCARBON HYDROXYLASES 1995-2014
History Note: 2015
DeCS ID: 55605
Unique ID: D065633
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2015/01/01
Date of Entry: 2014/06/26
Revision Date: 2016/05/27
Cytochrome P-450 CYP1B1 - Preferred
Concept UI M0590251
Scope note A cytochrome P450 aryl hydrocarbon hydroxylase that has specificity for ESTROGENS which it converts into 4-hydroxy estrogens. CYP1B1 has been shown to be physiologically important for FETAL DEVELOPMENT with mutations in the CYP1B1 gene resulting in congenital forms of GLAUCOMA and Peter's anomaly.
Preferred term Cytochrome P-450 CYP1B1
Entry term(s) Cytochrome P 450 CYP1B1
Cytochrome P450 CYP1B1
Cytochrome P450, Family 1, Subfamily B, Polypeptide 1
Cytochrome P4501B1
P450 CYP1B1, Cytochrome



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey