| Descriptor English: | 7-Alkoxycoumarin O-Dealkylase | ||||||
| Descriptor Spanish: |
7-Alcoxicumarina O-Dealquilasa
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| Descriptor Portuguese: | O-Dealquilase 7-Alcoxicumarina | ||||||
| Descriptor French: | 7-Alkoxycoumarin O-dealkylase | ||||||
| Entry term(s): |
7 Alkoxycoumarin O Dealkylase 7 Ethoxycoumarin Dealkylase 7 Ethoxycoumarin Hydroxylase 7 Ethoxycoumarin Monooxygenase 7 Ethoxycoumarin O De Ethylase 7 Ethoxycoumarin O Dealkylase 7 Ethoxycoumarin O Deethylase 7 Propoxycoumarin O Depropylase 7-Ethoxycoumarin Dealkylase 7-Ethoxycoumarin Hydroxylase 7-Ethoxycoumarin Monooxygenase 7-Ethoxycoumarin O-De-Ethylase 7-Ethoxycoumarin O-Dealkylase 7-Ethoxycoumarin O-Deethylase 7-Propoxycoumarin O-Depropylase Cytochrome P 450 Dependent O Dealkylase Cytochrome P-450-Dependent O-Dealkylase Dealkylase, 7-Ethoxycoumarin Deethylase, Ethoxycoumarin Ethoxycoumarin Deethylase Ethoxycoumarin O Deethylase Ethoxycoumarin O-Deethylase Hydroxylase, 7-Ethoxycoumarin Monooxygenase, 7-Ethoxycoumarin O-Deethylase, 7-Ethoxycoumarin O-Depropylase, 7-Propoxycoumarin P-450-Dependent O-Dealkylase, Cytochrome |
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| Tree number(s): |
D08.811.682.690.708.170.010.024 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D015660 | ||||||
| Scope note: | A drug-metabolizing enzyme found in the hepatic, placental and intestinal microsomes that metabolizes 7-alkoxycoumarin to 7-hydroxycoumarin. The enzyme is cytochrome P-450- dependent. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 1.14.13.- | ||||||
| Previous Indexing: |
Oxygenases (1966-1989) |
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| Public MeSH Note: | 90 |
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| History Note: | 90 |
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| DeCS ID: | 24513 | ||||||
| Unique ID: | D015660 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1990/01/01 | ||||||
| Date of Entry: | 1989/05/25 | ||||||
| Revision Date: | 2016/05/27 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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7-Alkoxycoumarin O-Dealkylase
- Preferred
| Concept UI |
M0023999 |
| Scope note | A drug-metabolizing enzyme found in the hepatic, placental and intestinal microsomes that metabolizes 7-alkoxycoumarin to 7-hydroxycoumarin. The enzyme is cytochrome P-450- dependent. |
| Preferred term | 7-Alkoxycoumarin O-Dealkylase |
| Entry term(s) |
7 Alkoxycoumarin O Dealkylase 7 Ethoxycoumarin Dealkylase 7 Ethoxycoumarin Hydroxylase 7 Ethoxycoumarin Monooxygenase 7 Ethoxycoumarin O De Ethylase 7 Ethoxycoumarin O Dealkylase 7 Ethoxycoumarin O Deethylase 7 Propoxycoumarin O Depropylase 7-Ethoxycoumarin Dealkylase 7-Ethoxycoumarin Hydroxylase 7-Ethoxycoumarin Monooxygenase 7-Ethoxycoumarin O-De-Ethylase 7-Ethoxycoumarin O-Dealkylase 7-Ethoxycoumarin O-Deethylase 7-Propoxycoumarin O-Depropylase Cytochrome P 450 Dependent O Dealkylase Cytochrome P-450-Dependent O-Dealkylase Dealkylase, 7-Ethoxycoumarin Deethylase, Ethoxycoumarin Ethoxycoumarin Deethylase Ethoxycoumarin O Deethylase Ethoxycoumarin O-Deethylase Hydroxylase, 7-Ethoxycoumarin Monooxygenase, 7-Ethoxycoumarin O-Deethylase, 7-Ethoxycoumarin O-Depropylase, 7-Propoxycoumarin P-450-Dependent O-Dealkylase, Cytochrome |
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