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Descriptor English: Metolazone
Descriptor Spanish: Metolazona
Descriptor metolazona
Scope note: Diurético derivado de la quinazolina-sulfonamida que actúa inhibiendo los SIMPORTADORES SODIO CLORO.
Descriptor Portuguese: Metolazona
Descriptor French: Métolazone
Entry term(s): Diulo
Microx
Mykrox
SR 720 22
SR-720-22
SR72022
Zaroxolyn
Tree number(s): D02.065.884.600
D02.886.590.700.600
D03.633.100.786.830.688
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D008788
Scope note: A quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antihypertensive Agents
Antihipertensivos
Anti-Hipertensivos
Antihypertenseurs
antihipertensivos
Diuretics
Diuréticos
Diuréticos
Diurétiques
diuréticos
Sodium Chloride Symporter Inhibitors
Inhibidores de los Simportadores del Cloruro de Sodio
Inibidores de Simportadores de Cloreto de Sódio
Inhibiteurs du symport chlorure sodium
inhibidores de los simportadores del cloruro de sodio
Registry Number: TZ7V40X7VX
CAS Type 1 Name: 6-Quinazolinesulfonamide, 7-chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-
Previous Indexing: Diuretics, Sulfamyl (1974)
Quinazolines (1971-1974)
Public MeSH Note: 91; was see under DIURETICS, SULFAMYL 1975-90
History Note: 91(75); was see under DIURETICS, SULFAMYL 1975-90
DeCS ID: 8978
Unique ID: D008788
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/11
Revision Date: 2017/05/24
Metolazone - Preferred
Concept UI M0013684
Scope note A quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
Preferred term Metolazone
Microx - Narrower
Concept UI M0350908
Preferred term Microx
Entry term(s) Mykrox
Zaroxolyn - Narrower
Concept UI M0350906
Preferred term Zaroxolyn
Diulo - Narrower
Concept UI M0350909
Preferred term Diulo
SR-720-22 - Narrower
Concept UI M0350907
Preferred term SR-720-22
Entry term(s) SR 720 22
SR72022



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