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Descriptor English: CDC2 Protein Kinase
Descriptor Spanish: Proteína Quinasa CDC2
Descriptor proteína cinasa CDC2
Entry term(s) cinasa 1 dependiente de ciclina
histona cinasa p34(cdc2)
proteincinasa Cdk1
proteína p34cdc2
Scope note: Fosfoproteína con actividad de proteína cinasa que funciona en la transición de la fase G2/M del CICLO CELULAR. Es la subunidad catalítica del FACTOR PROMOTOR DE MADURACION y forma complejos con la CICLINA A y con la CICLINA B de las células de los mamíferos. La actividad máxima de la cinasa 1 dependiente de ciclina se produce cuando está completamente desfosforilada.
Descriptor Portuguese: Proteína Quinase CDC2
Descriptor French: Protéine-kinase CDC2
Entry term(s): Cdk1 Protein Kinase
Cyclin Dependent Kinase 1
Cyclin-Dependent Kinase 1
Histone Kinase p34(cdc2)
Protein Kinase, CDC2
Protein Kinase, Cdk1
Protein p34cdc2
cdc2+ Protein
cdk1 Kinase
p34cdc2 Protein
p34cdc2, Protein
Tree number(s): D08.811.913.696.620.682.700.646.500.500.250
D08.811.913.696.620.682.700.646.500.984.500
D12.776.167.200.067.249
D12.776.167.200.580.500
D12.776.476.563.646.500.500.250
D12.776.476.563.646.500.984.500
D12.776.744.360
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016203
Scope note: Phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the CELL CYCLE. It is the catalytic subunit of the MATURATION-PROMOTING FACTOR and complexes with both CYCLIN A and CYCLIN B in mammalian cells. The maximal activity of cyclin-dependent kinase 1 is achieved when it is fully dephosphorylated.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.11.22
Previous Indexing: Phosphoproteins (1987-1990)
Public MeSH Note: 2004; see PROTEIN P34CDC2 1991-2003
History Note: 2004(1991)
DeCS ID: 29088
Unique ID: D016203
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1990/06/19
Revision Date: 2015/11/23
CDC2 Protein Kinase - Preferred
Concept UI M0024739
Scope note Phosphoprotein with protein kinase activity that functions in the G2/M phase transition of the CELL CYCLE. It is the catalytic subunit of the MATURATION-PROMOTING FACTOR and complexes with both CYCLIN A and CYCLIN B in mammalian cells. The maximal activity of cyclin-dependent kinase 1 is achieved when it is fully dephosphorylated.
Preferred term CDC2 Protein Kinase
Entry term(s) Cdk1 Protein Kinase
Cyclin Dependent Kinase 1
Cyclin-Dependent Kinase 1
Protein Kinase, CDC2
Protein Kinase, Cdk1
cdc2+ Protein
cdk1 Kinase
p34cdc2 Protein - Narrower
Concept UI M0442232
Preferred term p34cdc2 Protein
Entry term(s) Histone Kinase p34(cdc2)
Protein p34cdc2
p34cdc2, Protein



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