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Descriptor English: Crk-Associated Substrate Protein
Descriptor Spanish: Proteína Sustrato Asociada a CrK
Descriptor proteína sustrato asociada a CrK
Entry term(s) proteína BCAR1/p130Cas
proteína CRKAS
proteína Cas
Scope note: Proteína muy fosforilada de 130 kDa que se asocia con la PROTEÍNA ONCOGÉNICA CRK y con la PROTEÍNA ONCOGÉNICA SRC. Experimenta una FOSFORILACIÓN en la tirosina en las vías de señalización que regulan la MIGRACIÓN CELULAR y la PROLIFERACIÓN CELULAR.
Descriptor Portuguese: Proteína Substrato Associada a Crk
Descriptor French: Protéine BCAR1
Entry term(s): BCAR1 Protein
BCAR1 p130Cas Protein
Breast Cancer Anti Estrogen Resistance 1 Protein
Breast Cancer Anti-Estrogen Resistance 1 Protein
CRKAS Protein
Crk Associated Substrate
Crk Associated Substrate Protein
Crk-Associated Substrate
Protein, BCAR1 p130Cas
Protein, CRKAS
p130 Cas Protein
p130 Crk Associated Substrate
p130 Crk-Associated Substrate
p130Cas Protein
p130Cas Protein, BCAR1
Tree number(s): D12.644.360.024.282
D12.776.157.057.016
D12.776.476.024.316
D12.776.744.425
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050719
Scope note: A highly phosphorylated 130 kDa protein that associates with ONCOGENE PROTEIN CRK and ONCOGENE PROTEIN SRC. It undergoes tyrosine PHOSPHORYLATION in signaling pathways that regulate CELL MIGRATION and CELL PROLIFERATION.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; CRK-ASSOCIATED SUBSTRATE was indexed under PROTEINS 2004-2005
History Note: 2006(2004)
DeCS ID: 50765
Unique ID: D050719
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2017/12/13
Crk-Associated Substrate Protein - Preferred
Concept UI M0477396
Scope note A highly phosphorylated 130 kDa protein that associates with ONCOGENE PROTEIN CRK and ONCOGENE PROTEIN SRC. It undergoes tyrosine PHOSPHORYLATION in signaling pathways that regulate CELL MIGRATION and CELL PROLIFERATION.
Preferred term Crk-Associated Substrate Protein
Entry term(s) BCAR1 Protein
BCAR1 p130Cas Protein
Breast Cancer Anti Estrogen Resistance 1 Protein
Breast Cancer Anti-Estrogen Resistance 1 Protein
CRKAS Protein
Crk Associated Substrate
Crk Associated Substrate Protein
Crk-Associated Substrate
Protein, BCAR1 p130Cas
Protein, CRKAS
p130 Cas Protein
p130 Crk Associated Substrate
p130 Crk-Associated Substrate
p130Cas Protein
p130Cas Protein, BCAR1



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