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Descriptor English: Cimetidine
Descriptor Spanish: Cimetidina
Descriptor cimetidina
Scope note: Sustancia congénere de la histamina que inhibe competitivamente la unión de la HISTAMINA a los RECEPTORES HISTAMÍNICOS H2. La cimetidina presenta diversas acciones farmacológicas. Inhibe la secreción de ÁCIDO GÁSTRICO, así como la liberación de PEPSINA y GASTRINA.
Descriptor Portuguese: Cimetidina
Descriptor French: Cimétidine
Entry term(s): Altramet
Biomet
Biomet400
Cimetidine HCl
Cimetidine Hydrochloride
Eureceptor
HCl, Cimetidine
Histodil
Hydrochloride, Cimetidine
N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine
SK&F 92334
SK&F-92334
SK&F92334
SKF 92334
SKF-92334
SKF92334
Tagamet
Tree number(s): D02.078.370.200
D03.383.129.308.130
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002927
Scope note: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Ulcer Agents
Histamine H2 Antagonists
Cytochrome P-450 CYP1A2 Inhibitors
Registry Number: 80061L1WGD
CAS Type 1 Name: Guanidine, N-cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)-
Previous Indexing: Guanidines (1966-1977)
Imidazoles (1966-1977)
Public MeSH Note: 84; was see under GUANIDINES 1978-83
History Note: 84(78); was see under GUANIDINES 1978-83
DeCS ID: 2953
Unique ID: D002927
NLM Classification: QV 157
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1984/01/01
Date of Entry: 1977/04/22
Revision Date: 2016/05/28
Cimetidine - Preferred
Concept UI M0004479
Scope note A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
Preferred term Cimetidine
Entry term(s) N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine
Biomet - Narrower
Concept UI M0004481
Preferred term Biomet
Biomet400 - Narrower
Concept UI M0004482
Preferred term Biomet400
Cimetidine Hydrochloride - Narrower
Concept UI M0423990
Preferred term Cimetidine Hydrochloride
Entry term(s) Cimetidine HCl
HCl, Cimetidine
Hydrochloride, Cimetidine
Histodil - Narrower
Concept UI M0350952
Preferred term Histodil
SK&F-92334 - Narrower
Concept UI M0350951
Preferred term SK&F-92334
Entry term(s) SK&F 92334
SK&F92334
SKF 92334
SKF-92334
SKF92334
Tagamet - Narrower
Concept UI M0004483
Preferred term Tagamet
Altramet - Narrower
Concept UI M0004480
Preferred term Altramet
Eureceptor - Narrower
Concept UI M0350953
Preferred term Eureceptor



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