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Descriptor English: DNA Footprinting
Descriptor Spanish: Huella de ADN
Descriptor huella de ADN
Scope note: Método para determinar la especificidad de secuencias de las proteínas que se unen al ADN. La técnica de la huella del ADN utiliza un agente que daña el ADN (ya sea un reactivo químico o una nucleasa) que escinde el ADN en cada par de bases. Dicha escisión del ADN se inhibe en el lugar en que el ligando se une con el ADN.
Descriptor Portuguese: Pegada de DNA
Descriptor French: Prise d'empreintes sur l'ADN
Entry term(s): DNA Footprint
DNA Footprintings
DNA Footprints
Footprint, DNA
Footprinting, DNA
Footprintings, DNA
Footprints, DNA
Tree number(s): E05.393.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018983
Scope note: A method for determining the sequence specificity of DNA-binding proteins. DNA footprinting utilizes a DNA damaging agent (either a chemical reagent or a nuclease) which cleaves DNA at every base pair. DNA cleavage is inhibited where the ligand binds to DNA. (from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
Annotation: DNA FINGERPRINTING is available
Allowable Qualifiers: CL classification
EC economics
ES ethics
HI history
IS instrumentation
MT methods
SN statistics & numerical data
ST standards
TD trends
VE veterinary
Public MeSH Note: 96
History Note: 96
DeCS ID: 32770
Unique ID: D018983
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1996/01/01
Date of Entry: 1995/05/24
Revision Date: 2015/06/22
DNA Footprinting - Preferred
Concept UI M0028354
Scope note A method for determining the sequence specificity of DNA-binding proteins. DNA footprinting utilizes a DNA damaging agent (either a chemical reagent or a nuclease) which cleaves DNA at every base pair. DNA cleavage is inhibited where the ligand binds to DNA. (from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
Preferred term DNA Footprinting
Entry term(s) DNA Footprintings
Footprinting, DNA
Footprintings, DNA
Footprints, DNA - Related but not broader or narrower
Concept UI M0028353
Preferred term Footprints, DNA
Entry term(s) DNA Footprint
DNA Footprints
Footprint, DNA



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