DeCS

Descriptor English:

Squalene Monooxygenase

Descriptor Spanish:

Escualeno-Monooxigenasa

Spanish from Spain

Descriptor	escualeno-monooxigenasa
Entry term(s)	escualeno monooxigenasa
Scope note:	Segunda enzima en la vía encargada de la biosíntesis del COLESTEROL. Esta enzima cataliza la primera etapa de oxigenación en la biosíntesis de ESTEROLES y se cree que es una enzima limitante de la velocidad en esta vía. Específicamente, cataliza la converisón de ESCUALENO a (S)-escualeno-2,3-epóxido.

Descriptor Portuguese:

Esqualeno Mono-Oxigenase

Descriptor French:

Squalene monooxygenase

Entry term(s):

Squalene epoxidase
Squalene monooxygenase (2,3-epoxidizing)

Tree number(s):

D08.811.682.690.708.749

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D050603

Scope note:

The second enzyme in the committed pathway for CHOLESTEROL biosynthesis, this enzyme catalyzes the first oxygenation step in the biosynthesis of STEROLS and is thought to be a rate limiting enzyme in this pathway. Specifically, this enzyme catalyzes the conversion of SQUALENE to (S)-squalene-2,3-epoxide.

Allowable Qualifiers:

AD administration et posologie
AE effets indésirables
AI antagonistes et inhibiteurs
AN analyse
BI biosynthèse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
DE effets des médicaments et des substances chimiques
DF déficit
EC économie
GE génétique
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PH physiologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UL ultrastructure
UR urine

Registry Number:

EC 1.14.14.17

DeCS ID:

50664

Unique ID:

D050603

Documents indexed in the Virtual Health Library (VHL):

Click here to access the VHL documents

Date Established:

2006/01/01

Date of Entry:

2005/06/30