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Descriptor English: AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase
Descriptor Spanish: Dioxigenasa Dependiente de Alfa-Cetoglutarato, Homólogo 3 de AlkB
Descriptor dioxigenasa dependiente de alfa-cetoglutarato, homólogo 3 de AlkB
Entry term(s) antígeno de cáncer prostático 1
homólogo 3 de AlkB dioxigenasa dependiente de alfa-cetoglutarato
homólogo 3 de la proteína AlkB de reparación del ADN alquilado
Scope note: Una dioxigenasa y homólogo de reparación de los daños por alquilación que repara ADN que contiene 1-metiladenina (1meA) y 3-metilcitosina (3meC) mediante desmetilación oxidativa. Tiene gran afinidad por el ADN DE CADENA SIMPLE y también puede actuar sobre el ARN.
Descriptor Portuguese: Homólogo AlkB 3 da Dioxigenase Dependente de alfa-Cetoglutarato
Descriptor French: AlkB Homolog 3, alpha-ketoglutarate-dependent dioxygenase
Entry term(s): AlkB Homolog 3, Alpha Ketoglutarate Dependent Dioxygenase
Alkylated DNA Repair Protein AlkB Homolog 3
Alpha Ketoglutarate Dependent Dioxygenase AlkB Homolog 3
Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 3
Prostate Cancer Antigen 1
Tree number(s): D08.811.074.062.875
D08.811.682.690.416.139.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071500
Scope note: A dioxygenase and alkylation repair homolog that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. It has a strong preference for SINGLE-STRANDED DNA and may also act on RNA.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.14.11.-
Previous Indexing: DNA Repair Enzymes (2006-2016)
Dioxygenases (2006-2016)
Public MeSH Note: 2017
History Note: 2017
DeCS ID: 56461
Unique ID: D000071500
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/06
Revision Date: 2016/04/15
AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase - Preferred
Concept UI M000614942
Scope note A dioxygenase and alkylation repair homolog that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. It has a strong preference for SINGLE-STRANDED DNA and may also act on RNA.
Preferred term AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase
Entry term(s) AlkB Homolog 3, Alpha Ketoglutarate Dependent Dioxygenase
Alkylated DNA Repair Protein AlkB Homolog 3
Alpha Ketoglutarate Dependent Dioxygenase AlkB Homolog 3
Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 3
Prostate Cancer Antigen 1



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