Descriptor English: | AlkB Homolog 1, Histone H2a Dioxygenase | ||||||
Descriptor Spanish: |
Histona H2a Dioxigenasa, Homólogo 1 de AlkB
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Descriptor Portuguese: | Homólogo AlkB 1 da Histona H2a Dioxigenase | ||||||
Descriptor French: | AlkB Homolog 1, histone H2a dioxygenase | ||||||
Entry term(s): |
ABH1, Alpha-Ketoglutarate-Dependent Dioxygenase ABH1, DNA Lyase ALKBH Protein Alkylated DNA Repair Protein AlkB Homolog 1 Alpha Ketoglutarate Dependent Dioxygenase ABH1 Alpha-Ketoglutarate-Dependent Dioxygenase ABH1 DNA Lyase ABH1 DNA Oxidative Demethylase ALKBH1 |
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Tree number(s): |
D08.811.074.062.500 D08.811.682.690.416.139.500 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000071498 | ||||||
Scope note: | A dioxygenase and alkylation repair homolog that functions by oxidative demethylation in RNA and DNA REPAIR of substrates which contain 3-methylcytosine. It also functions as one of the HISTONE DEMETHYLASES involved in embryonic development and maintaining the pluripotency of EMBRYONIC STEM CELLS. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Registry Number: | EC 1.14.11.33 | ||||||
Previous Indexing: |
DNA Repair Enzymes (2005-2016) |
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Public MeSH Note: | 2017 |
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History Note: | 2017 |
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DeCS ID: | 56459 | ||||||
Unique ID: | D000071498 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2017/01/01 | ||||||
Date of Entry: | 2016/07/06 | ||||||
Revision Date: | 2016/04/15 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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AlkB Homolog 1, Histone H2a Dioxygenase
- Preferred
Concept UI |
M000614940 |
Scope note | A dioxygenase and alkylation repair homolog that functions by oxidative demethylation in RNA and DNA REPAIR of substrates which contain 3-methylcytosine. It also functions as one of the HISTONE DEMETHYLASES involved in embryonic development and maintaining the pluripotency of EMBRYONIC STEM CELLS. |
Preferred term | AlkB Homolog 1, Histone H2a Dioxygenase |
Entry term(s) |
ABH1, Alpha-Ketoglutarate-Dependent Dioxygenase ABH1, DNA Lyase ALKBH Protein Alkylated DNA Repair Protein AlkB Homolog 1 Alpha Ketoglutarate Dependent Dioxygenase ABH1 Alpha-Ketoglutarate-Dependent Dioxygenase ABH1 DNA Lyase ABH1 DNA Oxidative Demethylase ALKBH1 |
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