Search
Descriptor English: AlkB Homolog 8, tRNA Methyltransferase
Descriptor Spanish: Homólogo 8 de AlkB ARNt Metiltransferasa
Descriptor homólogo 8 de AlkB ARNt metiltransferasa
Entry term(s) ARNt (carboximetiluridina(34)-5-O)-metiltransferasa ABH8
homólogo 8 de AlkB reparadora de ADN alquilado
probable ABH8 dioxigenasa dependiente de alfa cetoglutarato
probable ABH8 dioxigenasa dependiente de alfacetoglutarato
tARN (carboximetiluridina(34)-5-O)-metiltransferasa ABH8
tRNA (carboximetiluridina(34)-5-O)-metiltransferasa ABH8
Scope note: Dioxigenasa y homólogo de la reparación de los daños por alquilación que cataliza la metilación de la 5-carboximetil URIDINA a 5-metilcarboximetil uridina en la posición de titubeo (wobble) del asa del ANTICODÓN en el ARN DE TRANSFERENCIA (ARNt) vía su dominio metiltransferasa. Tiene preferencia por el ARNt (ARGININA) y ARNt (GLUTAMATO) y no se une al ARNt (LISINA).
Descriptor Portuguese: Homólogo AlkB 8 da RNAt Metiltransferase
Descriptor French: AlkB Homolog 8, tRNA methyltransferase
Entry term(s): Alkylated DNA Repair Protein Alkb Homolog 8
Probable Alpha Ketoglutarate Dependent Dioxygenase ABH8
Probable Alpha-Ketoglutarate-Dependent Dioxygenase ABH8
S Adenosyl L Methionine Dependent tRNA Methyltransferase ABH8
S-Adenosyl-L-Methionine-Dependent tRNA Methyltransferase ABH8
tRNA (Carboxymethyluridine(34)-5-O)-Methyltransferase ABH8
Tree number(s): D08.811.682.690.416.139.984
D08.811.913.555.500.925.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071503
Scope note: A dioxygenase and alkylation repair homolog that catalyzes the methylation of 5-carboxymethyl URIDINE to 5-methylcarboxymethyl uridine at the wobble position of the ANTICODON loop in TRANSFER RNA (tRNA) via its methyltransferase domain. It has a preference for tRNA (ARGININE) and tRNA (GLUTAMATE), and does not bind tRNA (LYSINE).
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.14.11.-
Public MeSH Note: 2017
History Note: 2017
DeCS ID: 56502
Unique ID: D000071503
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/06
Revision Date: 2016/04/15
AlkB Homolog 8, tRNA Methyltransferase - Preferred
Concept UI M000614945
Scope note A dioxygenase and alkylation repair homolog that catalyzes the methylation of 5-carboxymethyl URIDINE to 5-methylcarboxymethyl uridine at the wobble position of the ANTICODON loop in TRANSFER RNA (tRNA) via its methyltransferase domain. It has a preference for tRNA (ARGININE) and tRNA (GLUTAMATE), and does not bind tRNA (LYSINE).
Preferred term AlkB Homolog 8, tRNA Methyltransferase
Entry term(s) Alkylated DNA Repair Protein Alkb Homolog 8
Probable Alpha Ketoglutarate Dependent Dioxygenase ABH8
Probable Alpha-Ketoglutarate-Dependent Dioxygenase ABH8
S Adenosyl L Methionine Dependent tRNA Methyltransferase ABH8
S-Adenosyl-L-Methionine-Dependent tRNA Methyltransferase ABH8
tRNA (Carboxymethyluridine(34)-5-O)-Methyltransferase ABH8



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey