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Descriptor English: Death Domain Superfamily
Descriptor Spanish: Superfamilia de los Dominios de Muerte
Descriptor superfamilia de los dominios de muerte
Entry term(s) dominio de tipo muerte
dominios de tipo muerte
Scope note: Familia de dominios de interacción con proteínas relacionadas estructuralmente que se caracterizan por tener un haz plegado cerrado de seis hélices, con topología en clave griega y una simetría interna en seudo doble pliegue. Los dominios de tipo muerte están presente en muchas proteínas que son fundamentales para la APOPTOSIS, entre ellas la PROTEÍNAS CON DOMINIOS DE INCLUSIÓN DE CASPASA y los RECEPTORES DE DOMINIOS DE MUERTE.
Descriptor Portuguese: Superfamília de Domínios de Morte
Descriptor French: Superfamille des domaines de mort
Entry term(s): Death Domain Superfamilies
Death Like Domain
Death Like Domains
Death-Like Domain
Death-Like Domains
Domain Superfamilies, Death
Domain Superfamily, Death
Superfamilies, Death Domain
Superfamily, Death Domain
Tree number(s): G02.111.570.820.709.275.750.500.395
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071458
Scope note: A family of structurally-related protein interaction domains characterized by 6-helical closed bundle fold, with Greek key topology and an internal pseudo two-fold symmetry. Death-like domains occur in many proteins that are essential for APOPTOSIS, including CASPASE RECRUITMENT DOMAIN CONTAINING PROTEINS and DEATH DOMAIN RECEPTORS.
Allowable Qualifiers: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Previous Indexing: Amino Acid Sequence (2001-2016)
Apoptosis (2001-2016)
Molecular Sequence Data (2001-2016)
Protein Structure, Tertiary (2007-2016)
Public MeSH Note: 2017
History Note: 2017
DeCS ID: 56745
Unique ID: D000071458
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/05/09
Death Domain Superfamily - Preferred
Concept UI M000614792
Scope note A family of structurally-related protein interaction domains characterized by 6-helical closed bundle fold, with Greek key topology and an internal pseudo two-fold symmetry. Death-like domains occur in many proteins that are essential for APOPTOSIS, including CASPASE RECRUITMENT DOMAIN CONTAINING PROTEINS and DEATH DOMAIN RECEPTORS.
Preferred term Death Domain Superfamily
Entry term(s) Death Domain Superfamilies
Death Like Domain
Death Like Domains
Death-Like Domain
Death-Like Domains
Domain Superfamilies, Death
Domain Superfamily, Death
Superfamilies, Death Domain
Superfamily, Death Domain



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