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Descriptor English: Panobinostat
Descriptor Spanish: Panobinostat
Descriptor panobinostat
Entry term(s) Farydak
LBH 589
LBH589
NVP LBH589
NVP-LBH589
Scope note: Derivado del ácido hidroxámico y de indol que actúa como inhibidor de las HISTONA DESACETILASAS. Se usa como antineoplásico en combinación con BORTEZOMIB y DEXAMETASONA para el tratamiento del MIELOMA MÚLTIPLE.
Descriptor Portuguese: Panobinostat
Descriptor French: Panobinostat
Entry term(s): LBH-589
LBH589
NVP-LBH589
Tree number(s): D02.092.570.394.535
D02.241.511.372.535
D03.633.100.473.746
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077767
Scope note: An indole and hydroxamic acid derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used as an antineoplastic agent in combination with BORTEZOMIB and DEXAMETHASONE for the treatment of MULTIPLE MYELOMA.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antineoplastic Agents
Histone Deacetylase Inhibitors
Registry Number: 9647FM7Y3Z
CAS Type 1 Name: 2-Propenamide, N-hydroxy-3-(4-(((2-(2-methyl-1H-indol-3-yl)ethyl)amino) methyl)phenyl)-, (2E)-
DeCS ID: 57746
Unique ID: D000077767
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/05/21
Panobinostat - Preferred
Concept UI M0540392
Preferred term Panobinostat
LBH589 - Narrower
Concept UI M0481330
Preferred term LBH589
Entry term(s) LBH-589
NVP-LBH589



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