ANATOMY Cells [A11] Cells Cellular Structures [A11.284] Cellular Structures Intracellular Space [A11.284.430] Intracellular Space Cell Nucleus [A11.284.430.106] Cell Nucleus Cell Nucleus Structures [A11.284.430.106.279] Cell Nucleus Structures Intranuclear Space [A11.284.430.106.279.345] Intranuclear Space Chromosomes [A11.284.430.106.279.345.190] Chromosomes Chromosome Structures [A11.284.430.106.279.345.190.160] Chromosome Structures Telomere [A11.284.430.106.279.345.190.160.845] Telomere Shelterin Complex [A11.284.430.106.279.345.190.160.845.500] Shelterin Complex Telomeric Repeat Binding Protein 1 [A11.284.430.106.279.345.190.160.845.500.500] Telomeric Repeat Binding Protein 1 Telomeric Repeat Binding Protein 2 [A11.284.430.106.279.345.190.160.845.500.750] Telomeric Repeat Binding Protein 2 CHEMICALS AND DRUGS Macromolecular Substances [D05] Macromolecular Substances Multiprotein Complexes [D05.500] Multiprotein Complexes Amyloid [D05.500.049] Amyloid Apoptosomes [D05.500.099] Apoptosomes Axin Signaling Complex [D05.500.117] Axin Signaling Complex Calcifying Nanoparticles [D05.500.135] Calcifying Nanoparticles COP9 Signalosome Complex [D05.500.139] COP9 Signalosome Complex Dynactin Complex [D05.500.142] Dynactin Complex Dystrophin-Associated Protein Complex [D05.500.149] Dystrophin-Associated Protein Complex Endosomal Sorting Complexes Required for Transport [D05.500.199] Endosomal Sorting Complexes Required for Transport Inflammasomes [D05.500.224] Inflammasomes Lactose Synthase [D05.500.299] Lactose Synthase Mechanistic Target of Rapamycin Complex 1 [D05.500.337] Mechanistic Target of Rapamycin Complex 1 Mechanistic Target of Rapamycin Complex 2 [D05.500.356] Mechanistic Target of Rapamycin Complex 2 Mediator Complex [D05.500.374] Mediator Complex Mitochondrial Permeability Transition Pore [D05.500.437] Mitochondrial Permeability Transition Pore Mitochondrial Precursor Protein Import Complex Proteins [D05.500.469] Mitochondrial Precursor Protein Import Complex Proteins Molecular Motor Proteins [D05.500.500] Molecular Motor Proteins Multienzyme Complexes [D05.500.562] Multienzyme Complexes NF-kappa B [D05.500.672] NF-kappa B Polycomb-Group Proteins [D05.500.781] Polycomb-Group Proteins Protein Translocation Systems [D05.500.890] Protein Translocation Systems Shelterin Complex [D05.500.918] Shelterin Complex Troponin [D05.500.945] Troponin CHEMICALS AND DRUGS Amino Acids, Peptides, and Proteins [D12] Amino Acids, Peptides, and Proteins Proteins [D12.776] Proteins DNA-Binding Proteins [D12.776.260] DNA-Binding Proteins Telomere-Binding Proteins [D12.776.260.735] Telomere-Binding Proteins Heterogeneous-Nuclear Ribonucleoprotein Group A-B [D12.776.260.735.500] Heterogeneous-Nuclear Ribonucleoprotein Group A-B Shelterin Complex [D12.776.260.735.625] Shelterin Complex Telomeric Repeat Binding Protein 1 [D12.776.260.735.750] Telomeric Repeat Binding Protein 1 Telomeric Repeat Binding Protein 2 [D12.776.260.735.875] Telomeric Repeat Binding Protein 2 CHEMICALS AND DRUGS Amino Acids, Peptides, and Proteins [D12] Amino Acids, Peptides, and Proteins Proteins [D12.776] Proteins Nuclear Proteins [D12.776.660] Nuclear Proteins Chromosomal Proteins, Non-Histone [D12.776.660.235] Chromosomal Proteins, Non-Histone Telomere-Binding Proteins [D12.776.660.235.700] Telomere-Binding Proteins Heterogeneous-Nuclear Ribonucleoprotein Group A-B [D12.776.660.235.700.500] Heterogeneous-Nuclear Ribonucleoprotein Group A-B Shelterin Complex [D12.776.660.235.700.625] Shelterin Complex Telomeric Repeat Binding Protein 1 [D12.776.660.235.700.750] Telomeric Repeat Binding Protein 1 Telomeric Repeat Binding Protein 2 [D12.776.660.235.700.875] Telomeric Repeat Binding Protein 2 CHEMICALS AND DRUGS Amino Acids, Peptides, and Proteins [D12] Amino Acids, Peptides, and Proteins Proteins [D12.776] Proteins Nucleoproteins [D12.776.664] Nucleoproteins Chromatin [D12.776.664.224] Chromatin Chromosomal Proteins, Non-Histone [D12.776.664.235] Chromosomal Proteins, Non-Histone Deoxyribonucleoproteins [D12.776.664.275] Deoxyribonucleoproteins Histones [D12.776.664.469] Histones Protamines [D12.776.664.750] Protamines RNA-Binding Proteins [D12.776.664.962] RNA-Binding Proteins Shelterin Complex [D12.776.664.981] Shelterin Complex Telomeric Repeat Binding Protein 1 [D12.776.664.981.500] Telomeric Repeat Binding Protein 1 Telomeric Repeat Binding Protein 2 [D12.776.664.981.750] Telomeric Repeat Binding Protein 2 PHENOMENA AND PROCESSES Genetic Phenomena [G05] Genetic Phenomena Genetic Structures [G05.360] Genetic Structures Chromosome Structures [G05.360.160] Chromosome Structures Telomere [G05.360.160.845] Telomere Shelterin Complex [G05.360.160.845.500] Shelterin Complex Telomeric Repeat Binding Protein 2 [G05.360.160.845.500.500] Telomeric Repeat Binding Protein 2

Shelterin Complex - Preferred

Concept UI	M000744989
Scope note	A TELOMERE cap complex consisting of telomere-specific proteins in association with telomeric DNA such as telomeric dsDNA-sDNA junction. They are involved in the protection of chromosome ends and TELOMERASE regulation and play a role in CELLULAR SENESCENCE and ageing-related pathology. In general it consists of six mostly TELOMERE-BINDING PROTEINS (POT1, RAP1, TIN2, TPP1, TRF1, and TRF2).
Preferred term	Shelterin Complex
Entry term(s)	Complex, POT1-TPP1 Shelterin Complex, Shelterin Complex, Telomere POT1-TPP1 POT1 TPP1 Shelterin Complex POT1-TPP1 Complex, Telomere POT1-TPP1 Shelterin Complex Shelterin Complex, POT1-TPP1 Telomere POT1 TPP1 Complex Telomere POT1-TPP1 Complex Telosome Telosomes

Telomere Cap Complex - Related but not broader or narrower

Concept UI	M000744993
Preferred term	Telomere Cap Complex

CST Complex - Related but not broader or narrower

Concept UI	M000744990
Preferred term	CST Complex
Entry term(s)	Capping Complex, Telomeric Complex, CST Complex, Ctc1-Stn1-Ten1 Complex, Telomeric Capping Ctc1 Stn1 Ten1 Complex Ctc1-Stn1-Ten1 Complex Telomeric Capping Complex

Telomeric Stn1-Ten1 Capping Complex - Related but not broader or narrower

Concept UI	M000744992
Preferred term	Telomeric Stn1-Ten1 Capping Complex
Entry term(s)	Telomeric Stn1 Ten1 Capping Complex