DeCS

Descriptor English:

Mitochondrial Precursor Protein Import Complex Proteins

Descriptor Spanish:

Proteínas del Complejo de Importación de Proteínas Precursoras Mitocondriales

Spanish from Spain

Descriptor	proteínas del complejo de importación de proteínas precursoras mitocondriales
Entry term(s)	canal TOM complejo MIA complejo MIM complejo SAM complejo TIM complejo TIM23 complejo TIMM complejo TOM complejo TOMM complejo de importación mitocondrial complejo de importación y ensamblaje del espacio intermembrana mitocondrial complejo de la maquinaria de clasificación y ensamblaje maquinaria TOMM proteínas de la maquinaria de importación de proteínas mitocondriales proteínas de la maquinaria de importación de proteínas precursoras mitocondriales translocasa TOM translocasa de la membrana mitocondrial externa translocasa del complejo de la membrana externa translocasa del complejo de la membrana interna translocasa del complejo de la membrana mitocondrial interna translocasas de proteínas precursoras mitocondriales translocasas del complejo de la membrana interna translocasas del complejo de la membrana interna 23
Scope note:	Complejos multiproteínicos que intervienen en la importación y la clasificación de preproteínas mitocondriales en uno de los cuatro subcompartimentos mitocondriales: la membrana externa, el espacio intermembrana, la membrana interna y la matriz. La maquinaria de importación de proteínas mitocondriales incluye el complejo translocasa de la membrana externa (TOM), el complejo translocasa de la membrana interna (TIM), el complejo de la vía del barril beta, el complejo de la vía de importación y ensamblaje del espacio intermembrana mitocondrial (MIA), las proteínas transportadoras de la membrana interna, el complejo TIM23 y el complejo de maquinaria de clasificación y ensamblaje (SAM).

Descriptor Portuguese:

Proteínas do Complexo de Importação de Proteína Precursora Mitocondrial

Descriptor French:

Protéines du complexe d'import des protéines précurseurs mitochondriales

Entry term(s):

Import Complex, Mitochondrial
MIA Complex
MIM Complex
Mitochondrial Import Complex
Mitochondrial Intermembrane Space Import and Assembly Complex
Mitochondrial Precursor Protein Import Machinery Proteins
Mitochondrial Preprotein Translocases
Mitochondrial Protein Import Machinery Proteins
Preprotein Translocases, Mitochondrial
SAM Complex
Sorting and Assembly Machinery Complex
TIM Complex
TIM23 Complex
TIMM Complex
TOM Channel
TOM Complex
TOM Translocase
TOMM Complex
TOMM Machinery
Translocase Outer Mitochondrial Membrane
Translocase of the Inner Membrane Complex
Translocase of the Inner Mitochondrial Membrane Complex
Translocase of the Outer Membrane Complex
Translocase, TOM
Translocases of the Inner Membrane 23 Complex
Translocases of the Inner Membrane Complex
Translocases, Mitochondrial Preprotein

Tree number(s):

D05.500.469
D05.500.890.563
D12.776.543.585.475.594
D12.776.575.750.594

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D000090622

Scope note:

Multiprotein complexes that mediate import and sorting of mitochondrial preproteins into one of the four mitochondrial subcompartments: the outer membrane, the intermembrane space, the inner membrane, and the matrix. Mitochondrial protein import machinery includes translocase of the outer membrane (TOM) complex, translocases of the inner membrane (TIM) complex, beta‐barrel pathway complex, the mitochondrial intermembrane space import and assembly (MIA) pathway complex, carrier proteins of the inner membrane and the TIM23 complex and sorting and assembly machinery (SAM) complex.

Allowable Qualifiers:

AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine

Concept UI	M000746905
Scope note	Multiprotein complexes that mediate import and sorting of mitochondrial preproteins into one of the four mitochondrial subcompartments: the outer membrane, the intermembrane space, the inner membrane, and the matrix. Mitochondrial protein import machinery includes translocase of the outer membrane (TOM) complex, translocases of the inner membrane (TIM) complex, beta‐barrel pathway complex, the mitochondrial intermembrane space import and assembly (MIA) pathway complex, carrier proteins of the inner membrane and the TIM23 complex and sorting and assembly machinery (SAM) complex.
Preferred term	Mitochondrial Precursor Protein Import Complex Proteins
Entry term(s)	Mitochondrial Precursor Protein Import Machinery Proteins Mitochondrial Protein Import Machinery Proteins

Concept UI	M000746910
Preferred term	Mitochondrial Preprotein Translocases
Entry term(s)	Preprotein Translocases, Mitochondrial Translocases, Mitochondrial Preprotein

Concept UI	M000746913
Preferred term	Mitochondrial Intermembrane Space Import and Assembly Complex
Entry term(s)	MIA Complex

Concept UI	M000746911
Preferred term	Translocase of the Outer Membrane Complex

Concept UI	M000746916
Preferred term	Sorting and Assembly Machinery Complex
Entry term(s)	SAM Complex

Concept UI	M000746917
Preferred term	Mitochondrial Import Complex
Entry term(s)	Import Complex, Mitochondrial MIM Complex

Concept UI	M0468589
Preferred term	TOM Complex
Entry term(s)	TOM Channel TOM Translocase TOMM Complex TOMM Machinery Translocase Outer Mitochondrial Membrane Translocase, TOM

Concept UI	M000746912
Preferred term	Translocases of the Inner Membrane Complex
Entry term(s)	TIM Complex TIMM Complex Translocase of the Inner Membrane Complex Translocase of the Inner Mitochondrial Membrane Complex

Concept UI	M000746915
Preferred term	Translocases of the Inner Membrane 23 Complex
Entry term(s)	TIM23 Complex

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