| Descriptor English: | PHEX Phosphate Regulating Neutral Endopeptidase | ||||
| Descriptor Spanish: |
Endopeptidasa Neutra Reguladora de Fosfato PHEX
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| Descriptor Portuguese: | Endopeptidase Neutra Reguladora de Fosfato PHEX | ||||
| Descriptor French: | PHEX Phosphate regulating neutral endopeptidase | ||||
| Entry term(s): |
PEX Phosphate Regulating Neutral Endopeptidase Phosphate Regulating Endopeptidase Homolog, X Linked Phosphate Regulating Endopeptidase Homolog, X-Linked Phosphate Regulating Neutral Endopeptidase X Linked Phosphate Regulating Endopeptidase Homolog X-Linked Phosphate Regulating Endopeptidase Homolog |
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| Tree number(s): |
D08.811.277.656.300.480.616 D08.811.277.656.675.374.616 D12.776.395.550.611 D12.776.543.550.607 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D053402 | ||||
| Scope note: | A membrane-bound metalloendopeptidase that may play a role in the degradation or activation of a variety of PEPTIDE HORMONES and INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS. Genetic mutations that result in loss of function of this protein are a cause of HYPOPHOSPHATEMIC RICKETS, X-LINKED DOMINANT. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Entry Combination: |
deficiency:Familial Hypophosphatemic Rickets
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| Registry Number: | EC 3.4.24.- | ||||
| Public MeSH Note: | 2007; PHEX PHOSPHATE REGULATING NEUTRAL ENDOPEPTIDASE was indexed under MEMBRANE GLYCOPROTEINS & METALLOENDOPEPTIDASES 2006, & PROTEINS 1995-2006 |
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| History Note: | 2007(1995) |
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| DeCS ID: | 52242 | ||||
| Unique ID: | D053402 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 2007/01/01 | ||||
| Date of Entry: | 2006/07/05 | ||||
| Revision Date: | 2013/07/10 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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PHEX Phosphate Regulating Neutral Endopeptidase
- Preferred
| Concept UI |
M0252450 |
| Scope note | A membrane-bound metalloendopeptidase that may play a role in the degradation or activation of a variety of PEPTIDE HORMONES and INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS. Genetic mutations that result in loss of function of this protein are a cause of HYPOPHOSPHATEMIC RICKETS, X-LINKED DOMINANT. |
| Preferred term | PHEX Phosphate Regulating Neutral Endopeptidase |
| Entry term(s) |
PEX Phosphate Regulating Neutral Endopeptidase Phosphate Regulating Endopeptidase Homolog, X Linked Phosphate Regulating Endopeptidase Homolog, X-Linked Phosphate Regulating Neutral Endopeptidase X Linked Phosphate Regulating Endopeptidase Homolog X-Linked Phosphate Regulating Endopeptidase Homolog |
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