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Descriptor English: Tubulin
Descriptor Spanish: Tubulina (Proteína)
Descriptor tubulina (proteína)
Entry term(s) alfa tubulina
alfa-tubulina
beta tubulina
beta-tubulina
delta tubulina
delta-tubulina
epsilon tubulina
epsilon-tubulina
gamma tubulina
gamma-tubulina
Scope note: Subunidad proteica de microtúbulos que se encuentra en grandes cantidades en el encéfalo de mamíferos. También se ha aislado del FLAGELO DEL ESPERMATOZOIDE, CILIOS y de otras fuentes. Estructuralmente, la proteína es un dímero con un peso molecular aproximado de 120.000 y un coeficiente de sedimentación de 5,8S. Se une a la COLCHICINA, VINCRISTINA y VINBLASTINA.
Descriptor Portuguese: Tubulina (Proteína)
Descriptor French: Tubuline
Entry term(s): alpha Tubulin
alpha-Tubulin
beta Tubulin
beta-Tubulin
delta Tubulin
delta-Tubulin
epsilon Tubulin
epsilon-Tubulin
gamma Tubulin
gamma-Tubulin
Tree number(s): D05.750.078.734.800
D12.776.220.600.800
D12.776.631.920
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D014404
Scope note: A microtubule subunit protein found in large quantities in mammalian brain. It has also been isolated from SPERM FLAGELLUM; CILIA; and other sources. Structurally, the protein is a dimer with a molecular weight of approximately 120,000 and a sedimentation coefficient of 5.8S. It binds to COLCHICINE; VINCRISTINE; and VINBLASTINE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Tubulin Modulators
Previous Indexing: Microtubules (1970-1974)
Nerve Tissue Proteins (1966-1974)
Public MeSH Note: 80; was see under GLYCOPROTEINS 1975-79
History Note: 80(75); was see under GLYCOPROTEINS 1975-79
DeCS ID: 14806
Unique ID: D014404
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1980/01/01
Date of Entry: 1974/11/11
Revision Date: 2015/11/24
Tubulin - Preferred
Concept UI M0022142
Scope note A microtubule subunit protein found in large quantities in mammalian brain. It has also been isolated from SPERM FLAGELLUM; CILIA; and other sources. Structurally, the protein is a dimer with a molecular weight of approximately 120,000 and a sedimentation coefficient of 5.8S. It binds to COLCHICINE; VINCRISTINE; and VINBLASTINE.
Preferred term Tubulin
gamma-Tubulin - Narrower
Concept UI M0022141
Preferred term gamma-Tubulin
Entry term(s) gamma Tubulin
delta-Tubulin - Narrower
Concept UI M0514734
Preferred term delta-Tubulin
Entry term(s) delta Tubulin
epsilon-Tubulin - Narrower
Concept UI M0514735
Preferred term epsilon-Tubulin
Entry term(s) epsilon Tubulin
alpha-Tubulin - Narrower
Concept UI M0022139
Preferred term alpha-Tubulin
Entry term(s) alpha Tubulin
beta-Tubulin - Narrower
Concept UI M0022140
Preferred term beta-Tubulin
Entry term(s) beta Tubulin



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