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Descriptor English: Platelet Factor 3
Descriptor Spanish: Factor Plaquetario 3
Descriptor factor plaquetario 3
Entry term(s) PF3
Scope note: Fosfolípido de la membrana plaquetaria que contribuye a la cascada de coagulación de la sangre al formar un complejo fosfolípido-proteína (TROMBOPLASTINA) que sirve como cofactor con el FACTOR VIIA para activar el FACTOR X en la vía extrínseca de la COAGULACIÓN DE LA SANGRE.
Descriptor Portuguese: Fator Plaquetário 3
Descriptor French: Facteur-3 plaquettaire
Entry term(s): Factor 3, Platelet
PF 3
Tree number(s): D12.776.124.125.691
D23.119.932
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010977
Scope note: A phospholipid from the platelet membrane that contributes to the blood clotting cascade by forming a phospholipid-protein complex (THROMBOPLASTIN) which serves as a cofactor with FACTOR VIIA to activate FACTOR X in the extrinsic pathway of BLOOD COAGULATION.
Annotation: a coagulant
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Coagulants
Registry Number: 37270-93-2
CAS Type 1 Name: Blood platelet factor 3
Previous Indexing: Blood Coagulation Factors (1974)
Blood Platelets (1974)
Lipoproteins (1974)
Public MeSH Note: 91; was see under BLOOD COAGULATION FACTORS 1975-90
History Note: 91(75); was see under BLOOD COAGULATION FACTORS 1975-90
DeCS ID: 22258
Unique ID: D010977
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2006/07/05
Platelet Factor 3 - Preferred
Concept UI M0017018
Scope note A phospholipid from the platelet membrane that contributes to the blood clotting cascade by forming a phospholipid-protein complex (THROMBOPLASTIN) which serves as a cofactor with FACTOR VIIA to activate FACTOR X in the extrinsic pathway of BLOOD COAGULATION.
Preferred term Platelet Factor 3
Entry term(s) Factor 3, Platelet
PF 3



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