| Descriptor English: | Transforming Growth Factors | ||||||
| Descriptor Spanish: |
Factores de Crecimiento Transformadores
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| Descriptor Portuguese: | Fatores de Crescimento Transformadores | ||||||
| Descriptor French: | Facteurs de croissance transformants | ||||||
| Entry term(s): |
Factor, Transforming Growth Factors, Transforming Growth Growth Factor, Transforming Growth Factors, Transforming Transforming Growth Factor |
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| Tree number(s): |
D12.644.276.963 D12.776.467.960 D23.529.960 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D015291 | ||||||
| Scope note: | Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA. |
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| Annotation: | general or unspecified; prefer specifics |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Registry Number: | 76057-06-2 | ||||||
| CAS Type 1 Name: | Animal growth regulators, transforming growth factors | ||||||
| Previous Indexing: |
Growth Substances (1966-1988) Peptides (1966-1988) |
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| Public MeSH Note: | 89 |
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| History Note: | 89 |
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| DeCS ID: | 23851 | ||||||
| Unique ID: | D015291 | ||||||
| NLM Classification: | QU 107 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1989/01/01 | ||||||
| Date of Entry: | 1988/05/24 | ||||||
| Revision Date: | 2015/06/02 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Transforming Growth Factors
- Preferred
| Concept UI |
M0023538 |
| Scope note | Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA. |
| Preferred term | Transforming Growth Factors |
| Entry term(s) |
Factor, Transforming Growth Factors, Transforming Growth Growth Factor, Transforming Growth Factors, Transforming Transforming Growth Factor |
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