| Descriptor English: | Agouti-Related Protein | ||||
| Descriptor Spanish: |
Proteína Relacionada con Agouti
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| Descriptor Portuguese: | Proteína Relacionada com Agouti | ||||
| Descriptor French: | Protéine apparentée à Agouti | ||||
| Entry term(s): |
AGRP Protein AGRT Protein Agouti Related Protein |
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| Tree number(s): |
D12.644.276.074 D12.776.467.074 D23.529.074 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D054369 | ||||
| Scope note: | A secreted protein of approximately 131 amino acids that is related to AGOUTI SIGNALING PROTEIN and is also an antagonist of MELANOCORTIN RECEPTOR activity. It is expressed primarily in the HYPOTHALAMUS and the ADRENAL GLAND. As a paracrine signaling molecule, AGRP is known to regulate food intake and body weight. Elevated AGRP has been associated with OBESITY. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Intercellular Signaling Peptides and Proteins (1998-2007) Receptors, Melanocortin (1997-2007) |
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| Public MeSH Note: | 2008; AGOUTI-RELATED PROTEIN was indexed under INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 1997-2007 |
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| History Note: | 2008 (1997) |
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| DeCS ID: | 52759 | ||||
| Unique ID: | D054369 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 2008/01/01 | ||||
| Date of Entry: | 2007/07/09 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Agouti-Related Protein
- Preferred
| Concept UI |
M0274612 |
| Scope note | A secreted protein of approximately 131 amino acids that is related to AGOUTI SIGNALING PROTEIN and is also an antagonist of MELANOCORTIN RECEPTOR activity. It is expressed primarily in the HYPOTHALAMUS and the ADRENAL GLAND. As a paracrine signaling molecule, AGRP is known to regulate food intake and body weight. Elevated AGRP has been associated with OBESITY. |
| Preferred term | Agouti-Related Protein |
| Entry term(s) |
AGRP Protein AGRT Protein Agouti Related Protein |
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