Descriptor English: | Midkine | ||||||
Descriptor Spanish: |
Midkina
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Descriptor Portuguese: | Midkina | ||||||
Descriptor French: | Midkine | ||||||
Entry term(s): |
Amphiregulin Associated Protein Amphiregulin-Associated Protein Cytokine MK |
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Tree number(s): |
D12.644.276.854 D12.776.467.848 D23.529.831 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000078792 | ||||||
Scope note: | A developmentally regulated, HEPARIN-binding secreted growth factor homologous to pleiotrophin (PTN). It regulates cell proliferation through its interaction with ANAPLASTIC LYMPHOMA KINASE (ALK) and is involved in the formation of NEOINTIMA following arterial injury. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Registry Number: | 137497-38-2 | ||||||
Public MeSH Note: | 2019; MIDKINE was indexed under CYTOKINES 2005-2018; and under CARRIER PROTEINS 1991-2004 |
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History Note: | 2019 (1991) |
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DeCS ID: | 57860 | ||||||
Unique ID: | D000078792 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2019/01/01 | ||||||
Date of Entry: | 2018/07/09 | ||||||
Revision Date: | 2018/06/19 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Midkine
- Preferred
Concept UI |
M0187737 |
Scope note | A developmentally regulated, HEPARIN-binding secreted growth factor homologous to pleiotrophin (PTN). It regulates cell proliferation through its interaction with ANAPLASTIC LYMPHOMA KINASE (ALK) and is involved in the formation of NEOINTIMA following arterial injury. |
Preferred term | Midkine |
Entry term(s) |
Amphiregulin Associated Protein Amphiregulin-Associated Protein Cytokine MK |
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