| Descriptor English: | Parathyroid Hormone-Related Protein | ||||||
| Descriptor Spanish: |
Proteína Relacionada con la Hormona Paratiroidea
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| Descriptor Portuguese: | Proteína Relacionada ao Hormônio Paratireóideo | ||||||
| Descriptor French: | Protéine apparentée à l'hormone parathyroïdienne | ||||||
| Entry term(s): |
Hormone-Related Protein, Parathyroid Hypercalcemic Factor, Tumor Hypercalcemic Hormone of Malignancy PTH Like Protein PTH Like Tumor Factor PTH Related Peptide PTH-Like Protein PTH-Related Peptide PTHrP Parathyroid Hormone Like Protein Parathyroid Hormone Like Tumor Factor Parathyroid Hormone Related Peptide Parathyroid Hormone Related Protein Parathyroid Hormone-Like Protein Parathyroid Hormone-Related Peptide Tumor Hypercalcemic Factor |
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| Tree number(s): |
D06.472.699.591 D12.644.276.908 D12.644.548.588 D12.776.467.890 D23.529.890 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D044162 | ||||||
| Scope note: | A ubiquitously expressed, secreted protein with bone resorption and renal calcium reabsorption activities that are similar to PARATHYROID HORMONE. It does not circulate in appreciable amounts in normal subjects, but rather exerts its biological actions locally. Overexpression of parathyroid hormone-related protein by tumor cells results in humoral calcemia of malignancy. |
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| Annotation: | see SCR for organism specific terms |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Pharm Action: |
Calcium-Regulating Hormones and Agents |
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| Previous Indexing: |
Peptide Hormones (2003) Proteins (1987-2002) |
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| Public MeSH Note: | 2004; PARATHYROID HORMONE-RELATED PROTEIN was indexed under PEPTIDE HORMONES 2003; PROTEINS 1987-2002 |
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| History Note: | 2004; use PARATHYROID HORMONE-RELATED PROTEIN (NM) 1987-2003 |
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| Entry Version: | PARATHYROID HORMONE RELAT PROTEIN |
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| Related: |
Parathyroid Hormone
MeSH Receptors, Parathyroid Hormone MeSH | ||||||
| DeCS ID: | 38111 | ||||||
| Unique ID: | D044162 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2004/01/01 | ||||||
| Date of Entry: | 2003/07/09 | ||||||
| Revision Date: | 2018/05/22 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Parathyroid Hormone-Related Protein
- Preferred
| Concept UI |
M0150746 |
| Scope note | A ubiquitously expressed, secreted protein with bone resorption and renal calcium reabsorption activities that are similar to PARATHYROID HORMONE. It does not circulate in appreciable amounts in normal subjects, but rather exerts its biological actions locally. Overexpression of parathyroid hormone-related protein by tumor cells results in humoral calcemia of malignancy. |
| Preferred term | Parathyroid Hormone-Related Protein |
| Entry term(s) |
Hormone-Related Protein, Parathyroid Hypercalcemic Factor, Tumor Hypercalcemic Hormone of Malignancy PTH Like Protein PTH Like Tumor Factor PTH Related Peptide PTH-Like Protein PTH-Related Peptide PTHrP Parathyroid Hormone Like Protein Parathyroid Hormone Like Tumor Factor Parathyroid Hormone Related Peptide Parathyroid Hormone Related Protein Parathyroid Hormone-Like Protein Parathyroid Hormone-Related Peptide Tumor Hypercalcemic Factor |
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