Search
Descriptor English: Wnt Proteins
Descriptor Spanish: Proteínas Wnt
Descriptor proteínas Wnt
Entry term(s) factor Wnt
proteína Wingless
proteína Wnt
Scope note: Las proteínas Wnt son una gran familia de glucoproteínas segregadas que desempeñan funciones esenciales en el DESARROLLO EMBRIONARIO Y FETAL y en el mantenimiento tisular. Se unen a los RECEPTORES FRIZZLED y actúan como FACTORES PROTEICOS PARACRINOS para iniciar diversas VÍAS DE TRANSDUCCIÓN DE SEÑALES. La vía de señalización canónica Wnt estabiliza al coactivador transcripcional BETA CATENINA.
Descriptor Portuguese: Proteínas Wnt
Descriptor French: Protéines de type Wingless
Entry term(s): Factor, Wnt
Protein, Wingless Type
Protein, Wnt
Type Protein, Wingless
Wingless Type Protein
Wingless Type Proteins
Wnt Factor
Wnt Factors
Wnt Protein
Tree number(s): D12.776.467.984
D23.529.984
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051153
Scope note: Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2006; WNT PROTEINS was indexed under INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 2005, & under PROTO-ONCOGENE PROTEINS 1987-2005
History Note: 2006(1987)
DeCS ID: 50759
Unique ID: D051153
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2020/05/27
Wnt Proteins - Preferred
Concept UI M0151350
Scope note Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.
Preferred term Wnt Proteins
Entry term(s) Factor, Wnt
Protein, Wingless Type
Protein, Wnt
Type Protein, Wingless
Wingless Type Protein
Wingless Type Proteins
Wnt Factor
Wnt Factors
Wnt Protein



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.


Go to survey