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Descriptor English: Probenecid
Descriptor Spanish: Probenecid
Descriptor probenecid
Scope note: El prototipo de agente uricosúrico. Inhibe la excreción renal de aniones orgánicos y reduce la reabsorción tubular de urato. El probenecid ha sido también utilizado en pacientes con disfunción renal y, debido a que reduce la excreción renal de otros fármacos, ha sido utilizado como adyuvante en el tratamiento antibacteriano.
Descriptor Portuguese: Probenecid
Descriptor French: Probénécide
Entry term(s): Benecid
Benemid
Benuryl
Pro-Cid
Probecid
Probenecid Weimer
Tree number(s): D02.065.884.625
D02.886.590.700.625
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011339
Scope note: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Adjuvants, Pharmaceutic
Uricosuric Agents
Registry Number: PO572Z7917
CAS Type 1 Name: Benzoic acid, 4-((dipropylamino)sulfonyl)-
DeCS ID: 27768
Unique ID: D011339
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/01
Probenecid - Preferred
Concept UI M0017601
Scope note The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
Preferred term Probenecid
Probenecid Weimer - Narrower
Concept UI M0475734
Preferred term Probenecid Weimer
Pro-Cid - Narrower
Concept UI M0475733
Preferred term Pro-Cid
Probecid - Narrower
Concept UI M0350911
Preferred term Probecid
Entry term(s) Benuryl
Benecid - Narrower
Concept UI M0475732
Preferred term Benecid
Benemid - Narrower
Concept UI M0017602
Preferred term Benemid



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