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Descriptor English: Terfenadine
Descriptor Spanish: Terfenadina
Descriptor terfenadina
Scope note: Antagonisa selectivo de los receptores H1 de histamina desprovisto de actividad depresora sobre el sistema nervioso central. Este fármaco se utilizó para el tratamiento de la ALERGIA pero se retiró por producir el SINDROME DEL QT LARGO.
Descriptor Portuguese: Terfenadina
Descriptor French: Terfénadine
Entry term(s): Balkis Saft Spezial
Cyater
Hisfedin
RMI 9918
RMI-9918
RMI9918
Rapidal
Seldane
Teldane
Terfedura
Terfemundin
Terfenadin AL
Terfenadin Heumann
Terfenadin Ratiopharm
Terfenadin Stada
Terfenadin Von Ct
Terfenadin-Ratiopharm
Terfenidine
Ternadin
Triludan
alpha-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperdinebutanol
Tree number(s): D02.455.426.559.389.115.800
D03.383.621.855
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016593
Scope note: A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Histamine H1 Antagonists, Non-Sedating
Registry Number: 7BA5G9Y06Q
CAS Type 1 Name: 1-Piperidinebutanol, alpha-(4-(1,1-dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-
Previous Indexing: Benzhydryl Compounds (1975-1991)
Histamine H1 Receptor Blockaders (1966-1991)
Piperidines (1966-1991)
Public MeSH Note: 92; TERFENADINE was indexed under BENZHYDRYL COMPOUNDS 1978-91
Online Note: use TERFENADINE (NM) to search TERFENADINE 1980-91
History Note: 92; was TERFENADINE (NM) 1978-91
DeCS ID: 29787
Unique ID: D016593
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1992/01/01
Date of Entry: 1991/01/25
Revision Date: 2017/05/24
Terfenadine - Preferred
Concept UI M0025307
Scope note A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.
Preferred term Terfenadine
Entry term(s) Terfenidine
alpha-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperdinebutanol
Ternadin - Narrower
Concept UI M0476203
Preferred term Ternadin
Balkis Saft Spezial - Narrower
Concept UI M0476191
Preferred term Balkis Saft Spezial
Rapidal - Narrower
Concept UI M0476194
Preferred term Rapidal
RMI-9918 - Narrower
Concept UI M0351835
Preferred term RMI-9918
Entry term(s) RMI 9918
RMI9918
Seldane - Narrower
Concept UI M0025308
Preferred term Seldane
Entry term(s) Teldane
Triludan
Terfedura - Narrower
Concept UI M0476196
Preferred term Terfedura
Terfemundin - Narrower
Concept UI M0476197
Preferred term Terfemundin
Terfenadin AL - Narrower
Concept UI M0476198
Preferred term Terfenadin AL
Terfenadin Heumann - Narrower
Concept UI M0476199
Preferred term Terfenadin Heumann
Terfenadin Stada - Narrower
Concept UI M0476200
Preferred term Terfenadin Stada
Terfenadin Von Ct - Narrower
Concept UI M0476201
Preferred term Terfenadin Von Ct
Terfenadin-Ratiopharm - Narrower
Concept UI M0476202
Preferred term Terfenadin-Ratiopharm
Entry term(s) Terfenadin Ratiopharm
Cyater - Narrower
Concept UI M0476192
Preferred term Cyater
Hisfedin - Narrower
Concept UI M0476193
Preferred term Hisfedin



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