Descriptor English: | Phencyclidine | ||||
Descriptor Spanish: |
Fenciclidina
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Descriptor Portuguese: | Fenciclidina | ||||
Descriptor French: | Phencyclidine | ||||
Entry term(s): |
1-(1-Phenylcyclohexyl)piperidine Angel Dust CL 395 CL-395 CL395 Dust, Angel GP 121 GP-121 GP121 Phencyclidine Hydrobromide Phencyclidine Hydrochloride Sernyl Serylan |
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Tree number(s): |
D03.383.621.699 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D010622 | ||||
Scope note: | A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust. |
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Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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Pharm Action: |
Enzyme Inhibitors Inhibidores Enzimáticos Inibidores Enzimáticos Antienzymes inhibidores enzimáticos Hallucinogens Alucinógenos Alucinógenos Hallucinogènes alucinógenos Excitatory Amino Acid Antagonists Antagonistas de Aminoácidos Excitadores Antagonistas de Aminoácidos Excitatórios Antagonistes des acides aminés excitateurs antagonistas de aminoácidos excitadores |
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Registry Number: | J1DOI7UV76 | ||||
CAS Type 1 Name: | Piperidine, 1-(1-phenylcyclohexyl)- | ||||
Previous Indexing: |
Anesthetics (1966-1972) Piperidines (1968-1972) |
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Public MeSH Note: | 73; was see under PIPERIDINES 1969-72; was see under PIPERIDINES & ANESTHETICS 1968; was see under ANESTHETICS 1967. |
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History Note: | 73(64); was see under PIPERIDINES 1969-72; was see under PIPERIDINES & ANESTHETICS 1968; was see under ANESTHETICS 1967 |
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Related: |
Phencyclidine Abuse
MeSH Receptors, Phencyclidine MeSH | ||||
DeCS ID: | 10812 | ||||
Unique ID: | D010622 | ||||
NLM Classification: | QV 77.7 | ||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
Date Established: | 1973/01/01 | ||||
Date of Entry: | 1999/01/01 | ||||
Revision Date: | 2016/05/31 |
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CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
|
Phencyclidine
- Preferred
GP-121
- Narrower
Serylan
- Narrower
Phencyclidine Hydrochloride
- Narrower
Sernyl
- Narrower
CL-395
- Narrower
Phencyclidine Hydrobromide
- Narrower
Concept UI |
M0016495 |
Scope note | A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust. |
Preferred term | Phencyclidine |
Entry term(s) |
1-(1-Phenylcyclohexyl)piperidine Angel Dust Dust, Angel |
Concept UI |
M0016496 |
Preferred term | GP-121 |
Entry term(s) |
GP 121 GP121 |
Concept UI |
M0016498 |
Preferred term | Serylan |
Concept UI |
M0329830 |
Preferred term | Phencyclidine Hydrochloride |
Concept UI |
M0016497 |
Preferred term | Sernyl |
Concept UI |
M0373872 |
Preferred term | CL-395 |
Entry term(s) |
CL 395 CL395 |
Concept UI |
M0329829 |
Preferred term | Phencyclidine Hydrobromide |
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