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Descriptor in English: Donepezil
Descriptor in Spanish: Donepezilo
Descriptor in Portuguese: Donepezila
Descriptor in French: Donépézil
Entry term(s): 1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride
Aricept
Donepezil Hydrochloride
Donepezilium Oxalate Trihydrate
E 2020
E-2020
E2020
Eranz
Tree number(s): D02.455.426.559.847.486.487.280
D03.383.621.238
D04.615.486.487.280
Scope note: An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
History Note: 2019 (1992)
DeCS UI: 57568
Descriptor UI: D000077265
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/07/03
Donepezil - Preferred
Concept UI M0206795
Scope note An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
Preferred term Donepezil
Eranz - Narrower
Concept UI M0477713
Preferred term Eranz
Donepezilium Oxalate Trihydrate - Narrower
Concept UI M0507746
Preferred term Donepezilium Oxalate Trihydrate
E 2020 - Narrower
Concept UI M0206796
Preferred term E 2020
Entry term(s) E-2020
E2020
Donepezil Hydrochloride - Narrower
Concept UI M0206791
Preferred term Donepezil Hydrochloride
Entry term(s) 1-Benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride
Aricept - Narrower
Concept UI M0206792
Preferred term Aricept



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