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Descriptor English: Plasminogen Activator Inhibitor 1
Descriptor Spanish: Inhibidor 1 de Activador Plasminogénico
Descriptor inhibidor 1 del activador del plasminógeno
Entry term(s) PAI-1
Scope note: Miembro de la familia serpina de las proteínas. Inhibe los activadores de plasminógeno de tipo tisula y del tipo de la urocinasa.
Descriptor Portuguese: Inibidor 1 de Ativador de Plasminogênio
Descriptor French: Inhibiteur-1 d'activateur du plasminogène
Entry term(s): E1, Serpin
PAI-1
Protein, SERPINE1
SERPINE1 Protein
Serpin E1
Type 1 Plasminogen Activator Inhibitor
Tree number(s): D12.644.861.695.500
D12.776.124.125.640
D12.776.872.695.500
D23.119.832.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017395
Scope note: A member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activators.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Serine Proteinase Inhibitors
Previous Indexing: Plasminogen Inactivators (1990-1992)
Public MeSH Note: 93; PAI-1 was see PLASMINOGEN INACTIVATORS 1990-92
Online Note: use PLASMINOGEN INACTIVATORS to search PAI-1 1990-92
History Note: 93; PAI-1 was see PLASMINOGEN INACTIVATORS 1990-92
Entry Version: PLASMINOGEN ACTIVATOR INHIB 1
DeCS ID: 30615
Unique ID: D017395
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1992/05/22
Revision Date: 2015/11/23
Plasminogen Activator Inhibitor 1 - Preferred
Concept UI M0026409
Scope note A member of the serpin family of proteins. It inhibits both the tissue-type and urokinase-type plasminogen activators.
Preferred term Plasminogen Activator Inhibitor 1
Entry term(s) E1, Serpin
PAI-1
Protein, SERPINE1
SERPINE1 Protein
Serpin E1
Type 1 Plasminogen Activator Inhibitor



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