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Descriptor English: Cytochrome P-450 CYP1A2
Descriptor Spanish: Citocromo P-450 CYP1A2
Descriptor citocromo P-450 CYP1A2
Entry term(s) CYP1A2
fenacetina O-desalquilasa
Scope note: Subtipo enzimático del citocromo P450 con especificidad para moléculas heteroaromáticas pequeñas relativamente planas, como la CAFEÍNA y el ACETAMINOFÉN.
Descriptor Portuguese: Citocromo P-450 CYP1A2
Descriptor French: Cytochrome P-450 CYP1A2
Entry term(s): CYP 1A2
CYP1A2
CYP1A2, Cytochrome P-450
Caffeine Demethylase
Cytochrome P 450 CYP1A2
Cytochrome P 450 LM4
Cytochrome P 450d
Cytochrome P-450 LM(4)
Cytochrome P-450 LM4
Cytochrome P-450d
Cytochrome P450 1A2
Demethylase, Caffeine
O-Dealkylase, Phenacetin
P-450 LM4, Cytochrome
Phenacetin O Dealkylase
Phenacetin O-Dealkylase
Tree number(s): D08.244.453.005.443
D08.244.453.100.750
D08.811.682.690.708.170.010.443
D08.811.682.690.708.170.020.750
D12.776.422.220.453.010.443
D12.776.422.220.453.100.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019388
Scope note: A cytochrome P450 enzyme subtype that has specificity for relatively planar heteroaromatic small molecules, such as CAFFEINE and ACETAMINOPHEN.
Annotation: do not confuse with other cytochrome P-450 CYP's
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Cytochrome P-450 CYP1A2 Inhibitors
Registry Number: EC 1.14.14.1
Previous Indexing: Cytochrome P-450 (1976-1996)
Oxidoreductases (1980-1996)
Phenacetin (1976-1980)
Public MeSH Note: 97; PHENACETIN O-DEALKYLASE was indexed under OXIDOREDUCTASES 1980-96, CYTOCHROME P-450 1976-96, & PHENACETIN 1976-80
Online Note: use CYTOCHROME P-450 CYP1A2 (NM) to search PHENACETIN O-DEALKYLASE 1980-96
History Note: 97; was PHENACETIN O-DEALKYLASE (NM) 1976-96
Related: Cytochrome P-450 CYP1A2 Inducers MeSH
DeCS ID: 33009
Unique ID: D019388
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1997/01/01
Date of Entry: 1996/06/24
Revision Date: 2016/05/27
Cytochrome P-450 CYP1A2 - Preferred
Concept UI M0028854
Scope note A cytochrome P450 enzyme subtype that has specificity for relatively planar heteroaromatic small molecules, such as CAFFEINE and ACETAMINOPHEN.
Preferred term Cytochrome P-450 CYP1A2
Entry term(s) CYP 1A2
CYP1A2
CYP1A2, Cytochrome P-450
Caffeine Demethylase
Cytochrome P 450 CYP1A2
Cytochrome P 450 LM4
Cytochrome P 450d
Cytochrome P-450 LM(4)
Cytochrome P-450 LM4
Cytochrome P-450d
Cytochrome P450 1A2
Demethylase, Caffeine
O-Dealkylase, Phenacetin
P-450 LM4, Cytochrome
Phenacetin O Dealkylase
Phenacetin O-Dealkylase



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