| Descriptor English: | Nuclear Receptor Subfamily 1, Group D, Member 1 | ||||||
| Descriptor Spanish: |
Miembro 1 del Grupo D de la Subfamilia 1 de Receptores Nucleares
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| Descriptor Portuguese: | Membro 1 do Grupo D da Subfamília 1 de Receptores Nucleares | ||||||
| Descriptor French: | Membre-1 du groupe D de la sous-famille-1 de récepteurs nucléaires | ||||||
| Entry term(s): |
NR1D1, Nuclear Receptor Nuclear Receptor NR1D1 Nuclear Receptors, Rev-erb-alpha Receptor NR1D1, Nuclear Rev erb alpha Nuclear Receptors Rev-erb-alpha Nuclear Receptors V erbA Related Protein EAR 1 V-erbA-Related Protein EAR-1 |
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| Tree number(s): |
D12.776.260.643.080 D12.776.476.156.300 D12.776.826.209.080 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D056953 | ||||||
| Scope note: | A DNA-binding orphan nuclear receptor that negatively regulates expression of ARNTL TRANSCRIPTION FACTORS and plays a role as a regulatory component of the circadian clock system. The Nr1d1 nuclear receptor expression is cyclically-regulated by a feedback loop involving its positive regulation by CLOCK PROTEIN; BMAL1 PROTEIN heterodimers and its negative regulation by CRYPTOCHROME and PERIOD PROTEINS. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
DNA-Binding Proteins (1990-2009) Receptors, Cytoplasmic and Nuclear (1990-2009) |
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| Public MeSH Note: | 2010 |
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| History Note: | 2010 |
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| DeCS ID: | 53640 | ||||||
| Unique ID: | D056953 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2010/01/01 | ||||||
| Date of Entry: | 2009/07/06 | ||||||
| Revision Date: | 2018/07/02 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Nuclear Receptor Subfamily 1, Group D, Member 1
- Preferred
| Concept UI |
M0533600 |
| Scope note | A DNA-binding orphan nuclear receptor that negatively regulates expression of ARNTL TRANSCRIPTION FACTORS and plays a role as a regulatory component of the circadian clock system. The Nr1d1 nuclear receptor expression is cyclically-regulated by a feedback loop involving its positive regulation by CLOCK PROTEIN; BMAL1 PROTEIN heterodimers and its negative regulation by CRYPTOCHROME and PERIOD PROTEINS. |
| Preferred term | Nuclear Receptor Subfamily 1, Group D, Member 1 |
| Entry term(s) |
NR1D1, Nuclear Receptor Nuclear Receptor NR1D1 Nuclear Receptors, Rev-erb-alpha Receptor NR1D1, Nuclear Rev erb alpha Nuclear Receptors Rev-erb-alpha Nuclear Receptors V erbA Related Protein EAR 1 V-erbA-Related Protein EAR-1 |
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