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Descriptor English: Nuclear Receptor Subfamily 2, Group C, Member 1
Descriptor Spanish: Miembro 1 del Grupo C de la Subfamilia 2 de Receptores Nucleares
Descriptor miembro 1 del grupo C de la subfamilia 2 de receptores nucleares
Scope note: Receptor nuclear huérfano de unión a ADN que tiene especificidad por secuencias AGGTCA repetidas directamente (RD). Se une al ADN, ya sea como homodímero o como heterodímero, con el receptor nuclear huérfano estrechamente relacionado MIEMBRO 2 DEL GRUPO C DE LA SUBFAMILIA 2 DE RECEPTORES NUCLEARES. La proteína fue identificada originalmente como proteína específica de la PRÓSTATA y está implicada en la regulación de una variedad de procesos celulares, que incluyen la DIFERENCIACIÓN CELULAR, PROLIFERACIÓN CELULAR y APOPTOSIS.
Descriptor Portuguese: Membro 1 do Grupo C da Subfamília 2 de Receptores Nucleares
Descriptor French: Membre-1 du groupe C de la sous-famille-2 des récepteurs nucléaires
Entry term(s): Nuclear Receptor NR2C1
Nuclear Receptor TR2
Orphan Nuclear Receptor NR2C1
Orphan Nuclear Receptor TR2
Receptor TR2, Nuclear
TR2 11 Receptor
TR2-11 Receptor
Tree number(s): D12.776.260.643.255
D12.776.826.209.255
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D057107
Scope note: A DNA-binding orphan nuclear receptor that has specificity for directly repeated (DR) AGGTCA sequences. It binds DNA as either as a homodimer or as a heterodimer with the closely-related orphan nuclear receptor NUCLEAR RECEPTOR SUBFAMILY 2, GROUP C, MEMBER 2. The protein was originally identified as a PROSTATE-specific protein and is involved in the regulation of variety of cellular processes, including CELL DIFFERENTIATION; CELL PROLIFERATION; and APOPTOSIS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2010; NUCLEAR RECEPTOR SUBFAMILY 2, GROUP C, MEMBER 1 was indexed under RECEPTORS, THYROID HORMONE 1995-2009
History Note: 2010(1995)
DeCS ID: 53645
Unique ID: D057107
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2015/06/23
Nuclear Receptor Subfamily 2, Group C, Member 1 - Preferred
Concept UI M0534634
Scope note A DNA-binding orphan nuclear receptor that has specificity for directly repeated (DR) AGGTCA sequences. It binds DNA as either as a homodimer or as a heterodimer with the closely-related orphan nuclear receptor NUCLEAR RECEPTOR SUBFAMILY 2, GROUP C, MEMBER 2. The protein was originally identified as a PROSTATE-specific protein and is involved in the regulation of variety of cellular processes, including CELL DIFFERENTIATION; CELL PROLIFERATION; and APOPTOSIS.
Preferred term Nuclear Receptor Subfamily 2, Group C, Member 1
Entry term(s) Nuclear Receptor NR2C1
Nuclear Receptor TR2
Orphan Nuclear Receptor NR2C1
Orphan Nuclear Receptor TR2
Receptor TR2, Nuclear
TR2 11 Receptor
TR2-11 Receptor



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