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Descriptor English: Nuclear Receptor Subfamily 4, Group A, Member 1
Descriptor Spanish: Miembro 1 del Grupo A de la Subfamilia 4 de Receptores Nucleares
Descriptor miembro 1 del grupo A de la subfamilia 4 de receptores nucleares
Scope note: Receptor nuclear huérfano estrechamente relacionado con los miembros de la familia de genes de los receptores de hormonas esteroideas y tiroideas. Fue identificado inicialmente en CÉLULAS NERVIOSAS y puede desempeñar un papel en la mediación de la DIFERENCIACIÓN CELULAR inducida por el FACTOR DE CRECIMIENTO NERVIOSO. Sin embargo, se han atribuido otras diversas funciones a esta proteína entre las que figura la regulación positiva y negativa de la APOPTOSIS.
Descriptor Portuguese: Membro 1 do Grupo A da Subfamília 4 de Receptores Nucleares
Descriptor French: Membre-1 du groupe A de la sous-famille-4 de récepteurs nucléaires
Entry term(s): Early Response Protein NAK1
NGFI B Orphan Nuclear Receptor
NGFI-B Orphan Nuclear Receptor
Nerve Growth Factor inducible B Protein
Nerve Growth Factor-inducible B Protein
Nuclear Receptor NR4A1
Nur77 Orphan Nuclear Receptor
Orphan Nuclear Receptor HMR
Orphan Nuclear Receptor NGFI B
Orphan Nuclear Receptor NGFI-B
Orphan Nuclear Receptor NR4A1
Orphan Nuclear Receptor TR3
TR3 Orphan Nuclear Receptor
Tree number(s): D12.776.260.643.400
D12.776.826.209.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D057105
Scope note: An orphan nuclear receptor that is closely related to members of the thyroid-steroid receptor gene family. It was originally identified in NERVE CELLS and may play a role in mediation of NERVE GROWTH FACTOR-induced CELL DIFFERENTIATION. However, several other functions have been attributed to this protein including the positive and negative regulation of APOPTOSIS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2010; ORPHAN NUCLEAR RECEPTOR NGFI-B (now NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 1) was indexed under DNA-BINDING PROTEINS and RECEPTORS, STEROID 2009, and under RECEPTORS, CYTOPLASMIC AND NUCLEAR and TRANSCRIPTION FACTORS 1991-2008
History Note: 2010(1991)
DeCS ID: 53647
Unique ID: D057105
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2015/07/08
Nuclear Receptor Subfamily 4, Group A, Member 1 - Preferred
Concept UI M0534631
Scope note An orphan nuclear receptor that is closely related to members of the thyroid-steroid receptor gene family. It was originally identified in NERVE CELLS and may play a role in mediation of NERVE GROWTH FACTOR-induced CELL DIFFERENTIATION. However, several other functions have been attributed to this protein including the positive and negative regulation of APOPTOSIS.
Preferred term Nuclear Receptor Subfamily 4, Group A, Member 1
Entry term(s) Early Response Protein NAK1
NGFI B Orphan Nuclear Receptor
NGFI-B Orphan Nuclear Receptor
Nerve Growth Factor inducible B Protein
Nerve Growth Factor-inducible B Protein
Nuclear Receptor NR4A1
Nur77 Orphan Nuclear Receptor
Orphan Nuclear Receptor HMR
Orphan Nuclear Receptor NGFI B
Orphan Nuclear Receptor NGFI-B
Orphan Nuclear Receptor NR4A1
Orphan Nuclear Receptor TR3
TR3 Orphan Nuclear Receptor



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