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Descriptor English: Nuclear Receptor Subfamily 2, Group C, Member 2
Descriptor Spanish: Miembro 2 del Grupo C de la Subfamilia 2 de Receptores Nucleares
Descriptor miembro 2 del grupo C de la subfamilia 2 de receptores nucleares
Scope note: Receptor nuclear huérfano que tiene especificidad por los elementos de la respuesta hormonal que se encuentra en los promotores de los genes diana. Se une al ADN, ya como homodímero o como heterodímero, con el receptor nuclear estrechamente relacionado MIEMBRO 1 DEL GRUPO C DE LA SUBFAMILIA 2 DE RECEPTORES NUCLEARES. La proteína fue identificada originalmente como proteína específica del TESTÍCULO y está implicada en la regulación de una variedad de procesos celulares, como es la DIFERENCIACIÓN CELULAR, PROLIFERACIÓN CELULAR y APOPTOSIS.
Descriptor Portuguese: Membro 2 do Grupo C da Subfamília 2 de Receptores Nucleares
Descriptor French: Membre-2 du groupe C de la sous-famille-2 de récepteurs nucléaires
Entry term(s): NR2C2, Nuclear Receptor
Nuclear Receptor NR2C2
Orphan Nuclear Receptor TR4
Receptor, TAK1
TAK1 Receptor
TR4 Nuclear Hormone Receptor
Testicular Receptor 4
Tree number(s): D12.776.260.643.327
D12.776.826.209.327
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D057125
Scope note: An orphan nuclear receptor that has specificity for hormone response elements found in the promoters of target genes. It binds DNA either as a homodimer or as heterodimer with the closely-related orphan nuclear receptor NUCLEAR RECEPTOR SUBFAMILY 2, GROUP C, MEMBER 1. The protein was originally identified as a TESTES-specific protein and is involved in the regulation of variety of cellular processes, including CELL DIFFERENTIATION; CELL PROLIFERATION; and APOPTOSIS.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Previous Indexing: Receptors, Steroid (2004-2009)
Receptors, Thyroid Hormone (2004-2009)
Public MeSH Note: 2010
History Note: 2010
DeCS ID: 53646
Unique ID: D057125
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2015/06/23
Nuclear Receptor Subfamily 2, Group C, Member 2 - Preferred
Concept UI M0534711
Scope note An orphan nuclear receptor that has specificity for hormone response elements found in the promoters of target genes. It binds DNA either as a homodimer or as heterodimer with the closely-related orphan nuclear receptor NUCLEAR RECEPTOR SUBFAMILY 2, GROUP C, MEMBER 1. The protein was originally identified as a TESTES-specific protein and is involved in the regulation of variety of cellular processes, including CELL DIFFERENTIATION; CELL PROLIFERATION; and APOPTOSIS.
Preferred term Nuclear Receptor Subfamily 2, Group C, Member 2
Entry term(s) NR2C2, Nuclear Receptor
Nuclear Receptor NR2C2
Orphan Nuclear Receptor TR4
Receptor, TAK1
TAK1 Receptor
TR4 Nuclear Hormone Receptor
Testicular Receptor 4



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