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Descriptor English: Nuclear Receptor Subfamily 1, Group F, Member 1
Descriptor Spanish: Miembro 1 del Grupo F de la Subfamilia 1 de Receptores Nucleares
Descriptor miembro 1 del grupo F de la subfamilia 1 de receptores nucleares
Scope note: Receptor nuclear huérfano de unión al ADN que regula positivamente la expresión de los FACTORES DE TRANSCRIPCIÓN ARNTL y es un componente regulador del sistema del reloj circadiano. La proteína tiene también un papel en la supervivencia y diferenciación celular de la neurona, en el sentido de que las mutaciones con pérdida de función de sus genes dan lugar a un fenotipo de ratón denominado como RATÓN ESTUPEFACTO.
Descriptor Portuguese: Membro 1 do Grupo F da Subfamília 1 de Receptores Nucleares
Descriptor French: Membre-1 du groupe F de la sous-famille-1 de récepteurs nucléaires
Entry term(s): NR1F1, Nuclear Receptor
Nuclear Receptor NR1F1
Nuclear Receptor ROR alpha
Nuclear Receptor ROR-alpha
Nuclear Receptor RZR alpha
Nuclear Receptor RZR-alpha
RAR Related Orphan Receptor A
RAR-Related Orphan Receptor A
RZR-alpha, Nuclear Receptor
Receptor NR1F1, Nuclear
Retinoid Related Orphan Receptor alpha
Retinoid Related Orphan Receptor alpha1
Retinoid Related Orphan Receptor alpha2
Retinoid Related Orphan Receptor alpha3
Retinoid Related Orphan Receptor alpha4
Retinoid-Related Orphan Receptor-alpha
Retinoid-Related Orphan Receptor-alpha1
Retinoid-Related Orphan Receptor-alpha2
Retinoid-Related Orphan Receptor-alpha3
Retinoid-Related Orphan Receptor-alpha4
Tree number(s): D12.776.260.643.100
D12.776.476.156.437
D12.776.826.209.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D057094
Scope note: A DNA-binding orphan nuclear receptor that positively regulates expression of ARNTL TRANSCRIPTION FACTORS and is a regulatory component of the circadian clock system. The protein also has a role in neuron cell survival and differentiation in that loss of function mutations of its gene result in the mouse phenotype referred to as the STAGGERER MOUSE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2010; RAR-RELATED ORPHAN RECEPTOR A (now NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 1) was indexed under TRANS-ACTIVATORS and RECEPTORS, CYTOPLASMIC AND NUCLEAR 1996-2009
History Note: 2010(1996)
DeCS ID: 53641
Unique ID: D057094
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2018/07/02
Nuclear Receptor Subfamily 1, Group F, Member 1 - Preferred
Concept UI M0534525
Scope note A DNA-binding orphan nuclear receptor that positively regulates expression of ARNTL TRANSCRIPTION FACTORS and is a regulatory component of the circadian clock system. The protein also has a role in neuron cell survival and differentiation in that loss of function mutations of its gene result in the mouse phenotype referred to as the STAGGERER MOUSE.
Preferred term Nuclear Receptor Subfamily 1, Group F, Member 1
Entry term(s) NR1F1, Nuclear Receptor
Nuclear Receptor NR1F1
Nuclear Receptor ROR alpha
Nuclear Receptor ROR-alpha
RAR Related Orphan Receptor A
RAR-Related Orphan Receptor A
Receptor NR1F1, Nuclear
Retinoid Related Orphan Receptor alpha
Retinoid-Related Orphan Receptor-alpha
Retinoid-Related Orphan Receptor-alpha4 - Narrower
Concept UI M0534697
Preferred term Retinoid-Related Orphan Receptor-alpha4
Entry term(s) Nuclear Receptor RZR alpha
Nuclear Receptor RZR-alpha
RZR-alpha, Nuclear Receptor
Retinoid Related Orphan Receptor alpha4
Retinoid-Related Orphan Receptor-alpha3 - Narrower
Concept UI M0534696
Preferred term Retinoid-Related Orphan Receptor-alpha3
Entry term(s) Retinoid Related Orphan Receptor alpha3
Retinoid-Related Orphan Receptor-alpha1 - Narrower
Concept UI M0534694
Preferred term Retinoid-Related Orphan Receptor-alpha1
Entry term(s) Retinoid Related Orphan Receptor alpha1
Retinoid-Related Orphan Receptor-alpha2 - Narrower
Concept UI M0534695
Preferred term Retinoid-Related Orphan Receptor-alpha2
Entry term(s) Retinoid Related Orphan Receptor alpha2



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