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Descriptor English: Receptors, Aryl Hydrocarbon
Descriptor Spanish: Receptores de Hidrocarburo de Aril
Descriptor receptores de hidrocarburos arílicos
Entry term(s) receptores AH
receptores TCDD
receptores de dioxinas
receptores de hidrocarburos de arilo
Scope note: Proteínas citoplasmáticas que unen ciertos aril hidrocarburos, los translocan hasta el núcleo, y activan la transcripción de segmentos particulares del ADN. Los receptores AH se identifican por su alta afinidad de unión a varios productos químicos ambientales que son carcinogénicos y teratogénicos entre los que se incluyen hidrocarburos aromáticos policíclicos que se encuentran en el humo del cigarro y en el smog, aminas heterocíclicas que se encuentran en los alimentos cocinados, e hidrocarburos halogenados entre los que se incluyen dioxinas y bifenilos policlorados. No se han identificado ligandos endógenos, pero se sospecha la existencia de un mensajero natural desconocido que desempeña un papel en la diferenciación y desarrollo celular.
Descriptor Portuguese: Receptores de Hidrocarboneto Arílico
Descriptor French: Récepteurs à hydrocarbure aromatique
Entry term(s): AH Receptor
AH Receptors
Aryl Hydrocarbon Receptor
Aryl Hydrocarbon Receptors
Dioxin Receptor
Dioxin Receptors
Polyaromatic Hydrocarbon Receptor
Polyaromatic Hydrocarbon Receptors
Receptor, AH
Receptor, Aryl Hydrocarbon
Receptor, Dioxin
Receptor, Polyaromatic Hydrocarbon
Receptor, TCDD
Receptors, 2,3,7,8-Tetrachlorodibenzo-p-dioxin
Receptors, AH
Receptors, Dioxin
Receptors, Polyaromatic Hydrocarbon
Receptors, TCDD
TCDD Receptor
TCDD Receptors
Tree number(s): D12.776.260.643.715
D12.776.826.209.715
D12.776.930.760
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018336
Scope note: Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Previous Indexing: Receptors, Drug (1979-1993)
Public MeSH Note: 94; ARYL HYDROCARBON RECEPTOR was indexed under RECEPTORS, DRUG 1981-93; 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN RECEPTOR was indexed under RECEPTORS, DRUG 1979-93
Online Note: use RECEPTORS, ARYL HYDROCARBON (NM) to search 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN RECEPTOR 1980-93 & ARYL HYDROCARBON RECEPTOR 1981-93
History Note: 94; was ARYL HYDROCARBON RECEPTOR (NM) 1981-93; 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN RECEPTOR was (NM) 1979-93
Entry Version: RECEPT ARYL HYDROCARBON
DeCS ID: 31140
Unique ID: D018336
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1994/01/01
Date of Entry: 1993/07/09
Revision Date: 2015/06/23
Receptors, Aryl Hydrocarbon - Preferred
Concept UI M0027573
Scope note Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected.
Preferred term Receptors, Aryl Hydrocarbon
Entry term(s) AH Receptor
AH Receptors
Aryl Hydrocarbon Receptor
Aryl Hydrocarbon Receptors
Dioxin Receptor
Dioxin Receptors
Polyaromatic Hydrocarbon Receptor
Polyaromatic Hydrocarbon Receptors
Receptor, AH
Receptor, Aryl Hydrocarbon
Receptor, Dioxin
Receptor, Polyaromatic Hydrocarbon
Receptor, TCDD
Receptors, 2,3,7,8-Tetrachlorodibenzo-p-dioxin
Receptors, AH
Receptors, Dioxin
Receptors, Polyaromatic Hydrocarbon
Receptors, TCDD
TCDD Receptor
TCDD Receptors



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